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Aussie cfs study/MRI scan abnormalities

Discussion in 'Latest ME/CFS Research' started by heapsreal, May 12, 2011.

  1. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    Study showing brain abnormalities in cfs, interesting, they even mention how sick we are without even taking into consideration our crappy immune system,

    CHRONIC FATIGUE SYNDROME
    BREAKTHROUGH BY INTERDISCIPLINARY
    ADELAIDE RESEARCH GROUP
    A team of independent Adelaide researchers has made a breakthrough
    in CFS research using new approaches to the analysis of magnetic
    resonance imaging (MRI) scans of the brain.
    Applying this to MRI scans of individuals with the much maligned
    chronic fatigue syndrome, they have discovered previously
    unsuspected changes in brain structure and function in CFS.
    Said Dr Richard Kwiatek, lead clinician of the group, Whilst
    acknowledging that our results need to be independently confirmed,
    they show striking changes in the midbrain which plays critical and
    primitive regulatory roles in the nervous system.
    We now know why patients with CFS are so sick: its because a very
    basic and important control centre in the brain is almost certainly
    affected. And this is without factoring in already known problems
    with their peripheral immune system.
    Traditionally, CFS sufferers have been viewed with suspicion by the
    medical and psychiatry establishments as the diagnosis of CFS is
    based on symptoms alone and no objective diagnostic test exists.
    Many individuals fight for years with insurance companies to be
    believed.
    Although objective changes have previously been detected in CFS,
    they require sophisticated and expensive research techniques, are not
    found in all individuals with the condition, and are more likely a
    consequence of the disease rather than its cause.
    The beauty of our technique is that, at least at the group level, it
    clearly demonstrates a difference in the functioning of the CFS brain
    and that of healthy individuals.
    The Adelaide teams study was funded by John T. Reid Charitable
    Trusts, supported by the Alison Hunter Memorial Foundation.
    It was today published online in the journal NMR in Biomedicine.
    Dr Kwiatek is available for further comment on 08 8267 1767.
    WillowJ likes this.
  2. Lynn

    Lynn Senior Member

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    Thanks for posting this heapsreal. It is very interesting research. One more study that shows there is something evidently physically wrong with us.

    Though my question is how many such studies do researchers need to do to prove that this is a real disease that needs real funding for research? I am so frustrated by it all! I am feeling a little disenchanted on this May 12th ME/CFS Awareness Day.

    Thanks for letting me rant.

    Lynn
  3. Esther12

    Esther12 Senior Member

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    I guess that depression etc would be likely to have physical differences in the brain too (edit - not that I'm saying I think this is anything like that - I've no idea. Just that there will be an ambiguity between neurology and psychology). Still, this is another piece of the puzzle, and will hopefully lead on to more work. It would be great to have a meaningful diagnostic test.
  4. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    I hear ya Lynn, it would be good to have all these cfs/me studies together and sit a heap of politicians down and make them read them and then ask them what are they going to do about it???
    Theres an aussie NK/natural killer cell study on cfs that finishes soon, not sure when results will be published but the people running the study are going overseas to talk about their results, so we will see what comes of that too, fingers crossed.
  5. anne_likes_red

    anne_likes_red Senior Member

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    Thanks for posting heaps :)

    Go the independant researchers!
  6. madietodd

    madietodd Senior Member

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    I find it amazing that there's structural change in the brain. I wonder what that looks like?
  7. ixchelkali

    ixchelkali Senior Member

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  8. Enid

    Enid Senior Member

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    Very interesting - thanks for posting heapsreal - always wanted to know quite what the "high spots" were in my own MRI brain scan.
  9. Snow Leopard

    Snow Leopard Senior Member

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    There was already a thread on this research:
    http://forums.phoenixrising.me/show...brainstem-dysfunction-amp-altered-homeostasis

    The paper is available in the usual place.

    The Hypothalamus observation was not strong.
    On the other hand, they also found.
    Which seems slightly worrying.

    There is also discussion about elevated heart rate, reduced heart rate variability while sleeping which relates to a previous paper I posted about.
  10. taniaaust1

    taniaaust1 Senior Member

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    The following comment of theirs "at least at group level" tells me that there wasnt "always obvious" difference between the controls and the ones with ME/CFS so hence this wont be able to be used for a diagnostic test.

    thanks heapsreal as that post cleared up something for me.. I knew the adelaide research team was still working together but wasnt 100% they were still using the name adelaide research team. They also are now obviously being funded differently to where they used to (years back used to have a bank as a trustee for a research fund which the SA CFS society helped them to set up, so the info i've put into the wiki in the past is now wrong..got to change it)
  11. taniaaust1

    taniaaust1 Senior Member

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    Im wondering if they will prospose anything to fix this abnormality they found?? (I may pay one of them a visit at some point and find out.. in the past he had no suggestions to give me on top of everything Im already doing).

    If any of their patients are about and going to see them soon, could you please pm me and let me know if they are doing anything new treatment wise in regards to that finding..

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