Posting this in both the 'Other News and Research' and 'MS' Forums. If the moderators feel a double posting is not necessary, please feel free to adjust how you deem appropriate. This looks like HUGE news! Wonder if it has implications for those of us in the ME group battling constantly with fungal infections and have brain damage as evidenced on MRI's. http://www.medicalnewstoday.com/articles/292734.php Excerpts: A drug used to treat athlete's foot and another to treat eczema have shown promise for reversing multiple sclerosis, a new study reveals. From screening the drugs. The team identified two - miconazole and clobetasol - that stimulated OPCs to produce myelin. Miconazole is an antifungal medication commonly used to treat skin infections, such as athlete's foot and jock itch. Clobetasol is a steroid used to treat eczema and other skin conditions. The researchers then injected these two compounds into mouse models of MS. They found that both drugs stimulated OPCs and enhanced myelination. What is more, they reversed paralysis in the mice, enabling them to use their back legs. Commenting on the findings, co-senior author Robert Miller, PhD, of the George Washington University School of Medicine in Washington, DC, says: "It was a striking reversal of disease severity in the mice. The drugs that we identified are able to enhance the regenerative capacity of stem cells in the adult nervous system. This truly represents a paradigm shift in how we think about restoring function to multiple sclerosis patients."