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As Needed Anti-Anxiety Treatments?

Discussion in 'General ME/CFS Discussion' started by Lyratic, Aug 18, 2017.

  1. Lyratic

    Lyratic

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    Hi there,

    After living with intense symptoms for years, I've decided that I want to try some sort of anti-anxiety treatment to help me through particularly bad days. I've had medical marijuana and Xanax recommended to me before, but I've never actually tried taking them. Does anyone have any experience with this, what works well, or how different medications or supplements might interact with ME or fibromyalgia?

    Thanks :)
     
  2. belize44

    belize44 Senior Member

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    I have been using Xanax on and off for nearly ten years. I find that it really helps me relax for sleep, but I don't use it in the daytime hours because a very small amount makes me incredibly drowsy. Of course there are dangers in that one can become dependent upon tranquilizers, so maybe medical marijuana would be a better choice?
     
    manasi12 likes this.
  3. Learner1

    Learner1 Professional Patient

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    About 75% of pharmaceutical drugs damage mitichondria, especially psychiatric drugs.

    Your symptoms are real, and you are wise to take action, but there are other choices...

    As background, an immediate family member went to 22 doctors, was on 9 psychiatric medications and was suicidal before we learned about alternatives to drugs. She became well and needs no drugs after 4 serious psychiatric diagnoses.

    Having a healthy gut, where most neurotransmitters are made, is important. Gluten sensitivity and food allergies, especially milk products can cause symptoms - gluten and dairy can act as excitotoxins in the brain.

    Deficiencies of B vitamins, particularly folate (MTHF or folinic acid), B6, and B12 can cause symptoms.

    GABA, suntheanine, and glycine are amino relatives you could try. And there are herbal, like ashwaganda, that might help.

    A good functional medicine doctor may be able to help you find answers here. Drugs may be a short term bandaid, but they are not a long term answer.
     
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  4. Snowdrop

    Snowdrop Rebel without a biscuit

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  5. Skippa

    Skippa Anti-BS

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    Hip likes this.
  6. Hip

    Hip Senior Member

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    echobravo and Skippa like this.
  7. Hip

    Hip Senior Member

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    Where may I ask did you read that?
     
  8. Learner1

    Learner1 Professional Patient

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    I didn't read it. It was presented by the researchers who'd tested the drugs at last year's United Mitochondrial Disease Foundation Conference in Seattle.

    Following which, Robert Naviaux, who'd given his Cell Danger Response talk just before that talk, got up and gave an impassioned speech to the 350 doctors in the audience to be cognizant of the risks to their delicate patients as they prescribed drugs.
     
  9. Hip

    Hip Senior Member

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    I very much doubt those researchers, because gathering evidence that even one drug might cause mitochondria damage takes a lot of effort and published studies, let alone making statements about the many thousands pharmaceutical drugs in existence.

    Even in the very short list of drugs with suspected mitochondria toxicity given in this post, there is only about 5 drugs in that list which have good evidence of such toxicity; the others are just suspected of causing toxicity.
     
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  10. Learner1

    Learner1 Professional Patient

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    @Hip Over time you've mentioned taking a lot of drugs, including psychiatric ones, and therefore have a vested interest in turning blind eye to the truth here.

    This wasn't some random group of wackos, it was a very serious set of researchers who went to great pains to describe the processes they'd used over several years to test each drug individually in order to build a database of mitochondrial toxins. I can't remember the name of it at the moment...but it was very real.

    And, I was one of the only people in the room without a doctorate degree. It was a serious exchange of information among serious professionals.

    Whether you choose to believe it or not is your business, but making light of this and recommending potentially harmful drugs to others here could do someone serious harm.

    Anything we put into our bodies has risks. We need to weigh the risks and potential rewards responsibly and with the best info possible before ingesting anything.
     
    CFS_for_19_years likes this.
  11. Hip

    Hip Senior Member

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    I have no vested interest in turning a blind eye to the truth. Rather, I am asking for details and evidence. So far you have not provided any: no names of researchers, no references to published studies, no links to this database of mitochondrial toxins that you mentioned. You expect me to believe, but you don't provide any information or evidence?

    To make unsupported statements such as "75% of pharmaceutical drugs damage mitochondria" is irresponsible.
     
  12. Learner1

    Learner1 Professional Patient

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    I gave the name of the conference and location. It was in June, 2016. I am satisfied with the facts as presented. You can look up who presented. You can look at the agenda for the last day of the conference, the one starting with Robert Naviaux of UCSD. Kendall Wallace of U Minn was the third presenter, if I recall correctly. You'd be looking for the second presenter, too. You can email them and ask for their slides.
     
    Last edited: Aug 19, 2017
  13. Learner1

    Learner1 Professional Patient

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    This article supports my statements, and there are many others as well...

    http://www.eurekaselect.com/140615

    A side note... my CFS was triggered by carboplatin and paclitaxel, which work by damaging mitochondria in cancer cells... As I unfortunately learned, they also damage healthy cells. No one told me this, and as my treatment began with emergency abdominal surgery, I was not in a state to do my own research and trusted my doctor completely. Now, my mitochondria are unhappy. THAT is irresponsible...

    Neither drug was on the list you provided. And, since you like links, here are but 2 articles... there are many more.

    https://www.google.com/url?q=http:/...ggeMAM&usg=AFQjCNGzU4WG391xNhMScQxGUrbKKLCLOw

    https://www.ncbi.nlm.nih.gov/pubmed/12459501
     
    Last edited: Aug 19, 2017
  14. Hip

    Hip Senior Member

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    The only thing I can find on the 2016 conference is this page of videos, and there nothing in the titles about mitochondrial damage or toxicity. I don't deny that some drugs may cause mitochondria damage, but to say 75% of drugs cause such damage is another story. You'd need provide peer reviewed published studies to properly back up a statement like that.

    But this discussion is taking the thread well off topic. The topic is about recommendations for anti-anxiety treatments.
     
  15. Learner1

    Learner1 Professional Patient

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    You took this thread off topic.:bang-head:

    I had stated that there are many valid alternatives to psychiatric drugs and gave examples.

    It makes no sense to take a drug that could be damaging mitochondria in the brain and adding to the illness. The brain uses a great amount of energy and reducing negative impacts to ATP production on mitochondria is critical to improved brain function and reducing symptoms.

    If symptoms are so bad as to prevent functioning to be able to solve the underlying problem, one could take it as a short term bandaid.

    But, diagnosing and treating food allergies, gut and microbiome abnormalities, toxicity, infections, and nutrient deficiencies is the way to solve psychiatric problems. No one has a Prozac, Neurontin, Ritalin, or Haldol deficiency... the brain and body are just asking for the proper ingredients to do the job properly.

    This article provides more insight and background on the topic of mitochondrial impacts of drugs:

    http://www.globalresearch.ca/mitochondrial-collateral-damage-thanks-to-big-pharma/5447650

    The resources of pharmaceutical companies to push their products are far greater than those of researchers, governments, or the common man. It is right to question sources, but ample info is available if you choose to look. From what I've seen, and was emphasized at the OMF Symposium, mitochondria are compromised in ME/CFS and we would be wise to avoid negatively impacting them further.
     
  16. Learner1

    Learner1 Professional Patient

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    Two resources that were tremendously helpful to my family in solving anxiety/depression issues are:

    https://www.amazon.com/Optimum-Nutrition-Mind-Patrick-Holford/dp/1591202590

    https://www.amazon.com/Primal-Body-Mind-Beyond-Health/dp/1594774137

    Best wishes...
     
  17. Hip

    Hip Senior Member

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    No, you took it off topic by saying that 75% of drugs damage mitochondria, which is an unsubstantiated statement, not backed up by any peer reviewed studies that you can supply, and likely wrong. So you are likely misinforming people.

    Now if you said that drugs like benzodiazepines can cause horrible withdrawal symptoms lasting for over 6 months in a subset of people, fine, that's good advice. Or if you mentioned that SSRI drugs can sometimes cause emotional flattening, that too is valid. But to argue that you should not take such anti-anxiety drugs on the basis of unsubstantiated claims about mitochondrial toxicity does not really help anyone.

    I agree there is a question mark regarding possible (but unproven) negative mitochondrial effects on some of the psychiatric drugs, such at those listed in my post that I linked to earlier. But these are only of possible concern to people with classic mitochondrial diseases, and I don't think there's much evidence that ME/CFS is such a mitochondrial disease. And even then, it's more the drugs like minocycline and metformin that are the main concern.
     
    Last edited: Aug 19, 2017
  18. jpcv

    jpcv Senior Member

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    Treat your gut, it helps a lot by reducing inflamation, inflamation in the brain is related to anxiety, depression and even autism
    You should see a doctor but I´ll give some brief explanations
    -short term, you can use something lie Alprazolam or Clonazepam. They work very fast but they can lead to long term side effects
    - When you have your anxiety controled, then you can take some antidepressive drug with anxiolitic properties, like escitalopram, Duloxetine.
    -Do you have insomnia? It is important to know because there ere some antidepressive drugds that help your sleep like trazodone or Valdoxan
    -psi therapy and something like yoga helps( I couldn´t tolerate yoga after I got ME but I used it before getting sick to treat my anxiety)

    I did everything I told you abocve, and it worked for me, now my necessity of drugs is very low
    Marijuana can have legal issues and i harmful too
     
  19. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    Medication-induced mitochondrial damage and disease
    http://sci-hub.cc/10.1002/mnfr.200700075
    Medications documented to induce mitochondrial damage:
    upload_2017-8-20_15-39-52.png
     
    Learner1 likes this.
  20. barbc56

    barbc56 Senior Member

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    Medication-induced mitochondrial damage and disease

    John Neustadt and Steve R. Pieczenik

    Montana Integrative Medicine, Bozeman, MT, USA

    My bold.
     

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