alex3619
Senior Member
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- 13,810
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- Logan, Queensland, Australia
Nobody knows how the ME trigger works. I have made some educated guesses as to what happens in cases like yours. I suspect the infection was just a minor bump, and the ME was already primed to go. One final infection and the immune system fell into the trap. I used to call this the two hit hypothesis, but its really a many hit hypothesis. Many patients get worse in stages, each infection driving them down some more. I suspect this happens before the symptoms become obvious as well, at least in some patients.
Coxsackie virus is a special case as it disseminates through muscle and other tissue, and may provoke things long after the acute phase is done.
Coxsackie virus is a special case as it disseminates through muscle and other tissue, and may provoke things long after the acute phase is done.