New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
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Article in journal mentions heat shock proteins and ME/CFS.

Discussion in 'Other Health News and Research' started by Gamboa, Jul 18, 2012.

  1. Gamboa

    Gamboa Senior Member

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    Below is the abstract from the journal " Cell Stress and Chaperones" in which mention is made of ME/CFS and heat shock proteins. It was published on-line July 14, 2012. Does anyone have access to the full paper?

    Biomedical and Life Sciences
    Cell Stress and Chaperones
    2012, DOI: 10.1007/s12192-012-0352-4

    Perspective and Reflection Article
    Loss of stress response as a consequence of viral infection: implications for disease and therapy

    Philip L. Hooper, Lawrence E. Hightower and Paul L. Hooper

    Abstract

    Herein, we propose that viral infection can induce a deficient cell stress response and thereby impairs stress tolerance and makes tissues vulnerable to damage. Having a valid paradigm to address the pathological impacts of viral infections could lead to effective new therapies for diseases that have previously been unresponsive to intervention. Host response to viral infections can also lead to autoimmune diseases like type 1 diabetes. In the case of Newcastle disease virus, the effects of viral infection on heat shock proteins may be leveraged as a therapy for cancer. Finally, the search for a specific virus being responsible for a condition like chronic fatigue syndrome may not be worthwhile if the disease is simply a nonspecific response to viral infection.
     
  2. Gamboa

    Gamboa Senior Member

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