The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
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Article: Genomic sequencing’s value challenged in Stanford study

Discussion in 'Other Health News and Research' started by RL_sparky, Mar 31, 2015.

  1. RL_sparky

    RL_sparky Senior Member

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    Article from January 2015
    http://www.sfgate.com/health/article/Scientists-say-environment-trumps-genetics-in-6018629.php
    Excerpt:
    “Genomics technology has advanced so much that we’re seeing an explosion in sequencing and analyzing this and that. Everything starts to look like genetics. And yet, it isn’t, really,” saidMark Davis, lead author of the study and director of Stanford’sInstitute for Immunity, Transplantation and Infection. “The big message is the environment matters a lot.”
    Davis’ study was specific to the immune system, but it’s likely, he said, that the same environmental influence applies to other body systemsfor instance, the nervous systemand overall health. And while there’s no doubt that genetics plays a huge role in certain diseases and health outcomes, the importance of DNA may be overstated.
    Genomic sequencing, which involves reading the genetic makeup of an organism, has become widespread in both research and consumer markets. Scientists are hunting for genetic clues to hundreds of human diseases, from Alzheimer’s and cancer to the flu, and increasingly researchers are promoting the idea of personalized medicine, or targeting treatment to a patient’s DNA.
    That’s all valuable work, Davis said. But he’s wary of overselling the potential of genomic sleuthing.
     
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  2. alex3619

    alex3619 Senior Member

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    There is a huge issue with big data and false positives. Just by chance you can find correlations in most big data sets for most problems. Only some of these will be other than chance. Genetics is the big fad ever since we got gene shears, automated sequencing etc. The new technology becomes the next big thing, then ubiquitous, then we understand it (after lots of false trails) and start looking to the next big thing.
     
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  3. WillowJ

    WillowJ คภภเє ɠรค๓թєl

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    There is DNA, then epigenetics (some of which is heritable, and some of which changes due to inputs), plus there are other factors not related at all. Personalized medicine is still a nice goal with an expanded set of factors (not only the DNA sequence), but we need more tech and maybe better ways of handling data. And there is still lots we don't know about metabolism, cellular communication, and so forth.
     
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  4. WillowJ

    WillowJ คภภเє ɠรค๓թєl

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    This bit was interesting (and more about this)
     
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  5. natasa778

    natasa778 Senior Member

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    There is a thread somewhere about CMV influence on individual's immune system being stronger than his/her genetic makeup
     
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