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Article from Stanford about ME/CFS 'Immune System Disruption'

Discussion in 'General ME/CFS News' started by aimossy, Oct 21, 2014.

  1. aimossy

    aimossy Senior Member

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    Last edited: Oct 21, 2014
  2. Sasha

    Sasha Fine, thank you

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    Thanks! Very interesting.

    ..."the primordial soup of creative disruption..." :wide-eyed:

    That's very welcome news - did we know this?

    "There will be blood" :eek:

    Seriously, this is an excellent article - very, very well written. And it looks as though it's in some kind of magazine for Stanford Medicine, so it will be going to a lot of people who we would like to influence.
     
  3. Bob

    Bob

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    It's news to me! Well spotted Sasha. Like you say, this is welcome news, if it works!
     
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  4. Valentijn

    Valentijn The Diabolic Logic

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    Are they going to be inviting Ian Lipkin to resubmit his proposal for a grant, now that the psychobabblers are supposedly not running the review process anymore?
     
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  5. Sidereal

    Sidereal Senior Member

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    Great to see an article like this in a mainstream publication. I would just object to referring to POTS as a "fainting disorder". As far as I'm aware most patients with POTS have never fainted (except maybe on a tilt table). I actually think this is one of the main reasons it's so hard to recognise that we have autonomic disorder. To most docs that just means syncope, the rest is "anxiety".

    LOL - so true. :rofl:
     
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  6. Sasha

    Sasha Fine, thank you

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  7. aimossy

    aimossy Senior Member

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    Seems to me that we have some proven quality researchers wanting to work on me/cfs with some big projects now - really hope that people with the illness get backing them with donations and being very loud with NIH about getting them funded. They cant use the excuse now that no one wants to research this illness. We have some ammunition with all this happening.
     
    Last edited: Oct 22, 2014
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  8. snowathlete

    snowathlete

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    Interpretation may depend on your definition of 'researchers familiar with the condition' though - it getting a mention in this article suggests people with a biological outlook but does anyone know for sure? psychiatrists could fit this definition if you have certain viewpoints.

    Would love to know more specifics.
     
  9. A.B.

    A.B. Senior Member

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    After watching some videos from the ME/CFS Symposion mentioned in the article, again I'm very impressed with Lipkin. At 17:52, he skipped a page about the differences between classical and atypical ME/CFS, saying that it was too complex. Does anyone know what the difference between classical and atypical ME/CFS is? Is it sudden infectious onset vs slow onset? Neurologic or non-neurologic symptoms?

    This page here:
     

    Attached Files:

    Last edited: Oct 21, 2014
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  10. Valentijn

    Valentijn The Diabolic Logic

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    According to the ICC I think ME can be "atypical" if there's no PEM at all, or if there is PEM but it isn't in response to physical exertion.
     
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  11. Forbin

    Forbin Senior Member

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    My understanding is that:

    ICC ME requires PENE and at least 7 other symptoms across 3 categories.
    ICC Atypical ME also requires PENE but (as I read it) only requires 5 other symptoms. [I'm not sure if you still need to have at least one symptom from the Energy metabolism/ion transportation category].
    http://www.name-us.org/DefintionsPages/DefinitionsArticles/2012 ICC Primer Short Form.pdf
     
    Last edited: Oct 23, 2014
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  12. Bob

    Bob

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    But we don't actually know what Prof Lipkin was referring to when he mentioned atypical ME, do we? He might have had something else specific in mind, other than the ICC. But i think it would be nice if he was referring to the ICC. It seems that he's had a lot of contact with Dr Montoya. Does Dr Montoya ever refer to atypical ME, or frequently use the ICC?
     
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  13. Forbin

    Forbin Senior Member

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    It's true; we don't know what Prof. Lipkin was referring to. It could be his own "in-house" brand of atypical ME.

    However, so far, the only other definition of "Atypical ME" that I've seen comes from the 2008 Pediatric Case Definition.
    This definition is only designed for those under 18 year of age.

    http://www.la-press.com/a-case-defi...phalomyelitischronic-f-article-a1147-abstract
     
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  14. A.B.

    A.B. Senior Member

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    Comparing adults and children to the same control group doesn't make sense so I doubt this refers to adult vs pediatric ME/CFS.
     
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  15. Little Bluestem

    Little Bluestem Senescent on the Illinois Prairie ❀❤✿Ƹ̵̡Ӝ̵̨̄Ʒ✿❤❀

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    :thumbsup::balloons::cool::balloons::)
    :D
     
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  16. ahimsa

    ahimsa Sick since 1990

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    I'm very slow but finally got around to reading this article (in fact, I'm only halfway through it).

    It's really one of the better articles that I've seen. Thanks so much for posting the link!
     

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