http://www.biomedcentral.com/1741-7015/11/205. The article discusses MS/ME and points to lots of similarities between the diseases. It also discusses the use of Rituximab for both, and points to that Rituximab has shown effect in MS and also other neuroimmune diseases. Could this imply that Rituximab-treatment is more likely to be effective in ME-patients with autoimmune disease like MS in the family, as that may suggest that their ME is of the autoimmune subset? I know that many of the participants in the Rituximab-trial either had diagnosis of autoimmune disease themselves or in their first line relatives. Anyone else who wants to speculate?