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Artesunate for HHV-6, anyone?

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by Sasha, Jul 17, 2013.

  1. Sasha

    Sasha Fine, thank you

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    Someone just mentioned this to me and I found there are some fairly old threads on it. Just wondering if anyone had good results and/or lack of side-effects using this for HHV-6? Doesn't seem to be much of a scientific literature on that specific topic. I'm wondering about this as a safer approach than Valcyte.
     
  2. vli

    vli

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    hi Sasha i am kind of interested in this too as frankly... i seem to be running out of options in terms of AVs (if my current cidofovir IVs do nothing for me). one person who tried it said they developed hearing loss and so stopped but from what i gather doesn't this have to be imported from china??? I live in hong kong which is why this person said i could try getting it in the first place. How would you get it in the UK?

    Edit: oh, i see online it says ?"In the UK, artesunate is available on a named patient basis only."
     
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  3. Sasha

    Sasha Fine, thank you

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    Artesunate is derived from artemisinin which seems to be available from health food stores but presumably also carries risks and I haven't read enough to know anything about that yet.
     
  4. Sasha

    Sasha Fine, thank you

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    A little bump...
     
  5. MEMum

    MEMum

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    Hi Sasha
    My daughter was prescribed artesunate at Breakspear for HHV-6 and HCMV, She also had an ongoing strep infection for which she was on injected penicillin. She did significantly improve for 3 months last year, after about 7 weeks on these. We then got diverted onto having a tonsillectomy as the ENT doc thought the tonsils could be the source of the strep infection.
    As an adult she is now under Dr Bansal. He doesn't reckon Artesunate does much...There are articles about it being an antiviral at least in vitro. It's easy to take and didn't have noticeable side effects. Unfortunately we haven't been able to replicate the improvement and she has since been diagnosed with antibodies to certain receptors in the basal ganglia.
    Hope this is useful
     
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  6. jstefl

    jstefl Senior Member

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    I used Hepasunate 50 from www.hepalin.com for a while. It contains 50 mg of pharmaceutical grade Artesunate.

    I did feel a definite benefit for a while, but once the methylation started kicking in, I no longer seemed to need it.

    It is expensive, $ 50.00 for 60 tablets, so that was my main consideration for stopping. I was also a bit leery of the warnings, so I took only three capsules a week. That was enough to make a noticeable difference in the way I felt, so I didn't push any harder.

    I had previously taken Valcyte, so I didn't need it for HHV-6.

    John
     
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  7. Sasha

    Sasha Fine, thank you

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    Thanks, MEMum - it's interesting to hear Dr Bansal's view. I hope your daughter is doing better these days.
     
  8. Sasha

    Sasha Fine, thank you

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    Thanks - that's interesting that you felt a benefit but it sounds as though you had maybe already cleared up your HHV-6. Nothing is simple!
     
  9. redaxe

    redaxe Senior Member

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    Just bumping this thread to see if anyone has tried Artesunate lately?

    It is a drug mentioned by the HHV6 Foundation as being active in vitro against HHV6 but I gather there is still a lack of trials on CFS.
    http://hhv-6foundation.org/clinicians/hhv-6-treatment
     
  10. Ema

    Ema Senior Member

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    I actually just restarted artesunate. I'm using much higher doses this time around as it seems like that is the key for those who report success. I believe Myhill recommends 2 mg/kg. At this dose, it gets expensive in a hurry!

    I'm also pulsing 4 days on and 3 days off. I'm not sure if this is necessary with the artesunate form though. If anyone knows If artemisinin and artesunate differ in this regard, it'd be great to know.
     
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  11. redaxe

    redaxe Senior Member

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    Thanks please keep us updated on this. We need some more focus on artesunate. It is supposed to be able to block the low level smoldering or early antigens that are hypothesized to be the problem with HHV6 so theoretically at the correct dosage one could assume it would work faster than Valcyte and maybe with less side-effects.
     

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