I only found relief from Artesunate when I followed Myhill's dosage: http://drmyhill.co.uk/wiki/Chronic_infections_in_CFS#Using_Artesunate which is much higher than Cheney's (4 times the Cheney dosage for my body weight). I had no improvement from the 50mg dosing. From the high level research that I did, it appears to fight cmv and hhv6: http://www.springerlink.com/content/xydqhqe88lu6p7nu/ http://cid.oxfordjournals.org/content/47/6/804.full. I plan to stay on the treatment for another 2 weeks, take 2 weeks off to detox (I don't take any antioxidants while on it as I understand that counteracts the treatment) and then return for another 3 months and continue until I no longer require it. About 3 weeks ago, it appeared that my immune systems woke up as I had lymph node pain for several days. Following that, general energy has steadily gone up to the point that I don't require the amount of sleep that I did even before I got sick (before this I needed 8-9 average to feel rested. The past week, I have averaged 5 and felt fine. With regard to the liver issues/hepatitis, there does appear to be some risk but it appears to be with people who took very high doses and in the reports I have found, the subjects returned to normal after ceasing treatment (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5831a3.htm). Valcyte in my opinion is riskier as it is a known carcinogen as reported to me by my MD when I initially asked for it and is part of the write up on the drug in Canada: http://www.rochecanada.com/fmfiles/...dPublicAdvisories/Valcyte/valcyteJune1HPE.pdf. (I would rather risk a reversible disease vs cancer). I would say I am probably a 9 right now. General energy is excellent. I still have some ill effects from exercise but is significantly reduced and it appears to be going down steadily. I try jogging once a week to see what happens. When I no longer feel the fatigue and chest tightness that exercise has historically created since getting ill, I will consider myself functionally cured. My goal is to eradicate this if at all possible at the lowest possible risk. So far, so good. P.S. I have also adopted 3 years ago a low carbohydrate diet with no sugar. Other than that, I am currently taking no other supplements except some probiotics due to the fact that I am probably killing a lot of good bacteria also.