I'm stable on a dose of 50mg 2 or 3 times a week now. It should be 3x but I developed hormonal problems (which I'm really not sure have anything to do with Artesunate but I am taking it easy on the drug just in case). I'm not getting any obvious "die off" reaction to the Artusunate in the last 3 /4 weeks. My husband (who doesn't know about this new drug) asked if I had been taking anything extra or new. He noticed that my recovery time from exercise or physical overexertion is now slightly better in the last 3 weeks. Artesunate is the only new thing I am taking. I haven't tried the wormwood swish as yet. Earlier use of wormwood had no noticable good effects on my health and I had severe sleep disturbances/vivid dreams from it earlier. May give it a go at some point again.