I'm not sure. I did urinary amino acids (Doctor's Data: UAA) beforehand and was low low low. After 2 1/2 months of Aminosyn, I decided I wanted first to run plasma aminos (Doctor's Data) to see if the blood, at least, was okay, and it was. I redid the plasma about a month later, because the 1st test showed very high methionine and glycine and I had been having liver issues and wanted to see if I'd addressed them adequately with P5P. Then, after the 2nd urinary amino acid test came back normal (but a little bit low in some aminos), I did a UAA and I was still very low. I had to run it really slow or I got headaches and dizziness. Also, I found that it was stimulating; wasn't sure if it was excitotoxicity, or if it was the EDTA or DMPS also in most of the I.V.'s, or the additional minerals, or the neural therapy. So many things were done at once! I rarely slept the night of a treatment. The i.v.'s by themselves did not usually keep me up though. I read in an old Genova Lab Functional Assessment Resource Manual (when they were GSDL), that normal plasma aminos together with low urinary aminos and low 24hour creatinine indicates 'subnormal renal clearance.' Not sure what 'subnormal' means. They say the opposite is seen in abnormally high renal clearance.