I have been interested in the issue of low amino acids (on UAA test) in PWC's because I have been low for years. Even when I felt great in 2007 and could do aerobic exercise and put in a full day, I was still low, and eating more protein did not make any difference. In fact, it just seemed to lower my levels, except for products of amino acid catabolism such as ammonia. Now I have learned about an amino acid product called SON Formula or MAP (master amino acid pattern) which has been developed by researchers looking at net nitrogen utilization. What they did over 34 years of research was study what happens to various proteins as they go into the body by measuring the nitrogen content of feces and urine. They found that a certain ratio of amino acids has a 99% utilization -- that is only 1% gets burned up into nitrogen and excreted. This is the product they are now marketing. I have not yet tried using it, but I am thinking of trying it. It seems to me that if this product works for people with the amino acid imbalances in ME-CFS (not studied by the research team), we should get increased anabolism --e.g. stronger muscles -- as the product would not be catabolized for energy in the Kreb's cycle as our other dietary proteins. Perhaps the ability to do a bit more physical activity would result. Perhaps PEM would reduce as our body had the nutrition to quickly repair the damage to tissues from exercise. If you have tried it and gotten good or poor or no results, please let me know. If you are interested in trying it, also let me know. The company has offered me a case discount and I am thinking it would be interesting to do an informal study if enough people are interested in trying it.