Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Are we sure that ME/CFS isn't Lambert-Eaton myasthenic syndrome (LEMS)?

Discussion in 'General ME/CFS Discussion' started by trails, Nov 11, 2015.

  1. trails

    trails Senior Member

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    merylg, Hutan, SB_1108 and 1 other person like this.
  2. lnester7

    lnester7 Seven

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    Too many patients do not have / develop lung cancer???
     
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  3. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    Goodness - they do look very similar, don't they? It wouldn't surprise me if some people with this illness are misdiagnosed with ME/CFS - maybe some people here? I had never heard of it, but did a search for more-authoritative pages (you can't be sure that Wikipedia entries are written by knowledgeable people, although they are generally good) and got this one.

    A few things about the illness suggest that I don't have it, e.g. the advisability of treating with acetylcholinesterase (AChE) inhibitors. I do better with anticholinergic drugs, which have the opposite effect, and some tests in the early days of my illness found my AChE levels to be a little low. I had asked for the tests because of a suspicion that my symptoms were due to organophosphate flea treatments used on my cats.

    The page also says that magnesium is contraindicated, whereas many people with ME seem to benefit from magnesium.
     
    Last edited: Nov 11, 2015
  4. ukxmrv

    ukxmrv Senior Member

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    It doesn't occur in outbreaks like ME did in the 20th century

    It doesn't suddenly appear in previously well people who suddenly get a virus infection and never recover

    With "ME/CFS" it always depends on what you are talking about, which criteria etc. Sure to be a misdiagnosis or two in there
     
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  5. trails

    trails Senior Member

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    Probably a stupid thread :thumbdown: I'm not usually susceptible to hypochondriasis or medical-students disease, or whatever. Nevertheless, elements of this disease kind of freaked me out a bit. My mother had ME/CFS symptoms for most of her adult life. Eventually, she passed away from lung cancer more than 15 years after she quit smoking.

    Given that I smoked for about 30 years before quitting, I'm undoubtedly guilty of a momentary panic attack. :nervous:
     
  6. Valentijn

    Valentijn Senior Member

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    In addition to the points raised above, I see no mention of anything resembling PEM. In fact:
    My muscles get weaker during use, not stronger.
     
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  7. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    My mother died of lung cancer, but I have no idea whether she had any symptoms like this, as I was very young when she died. I smoked for about 15 years. Stopped in the early 1980s. But I don't think I have this, as I said.
     
  8. Hutan

    Hutan Senior Member

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    Not a stupid thread.
    Bringing this to the attention of people may help someone. Thanks for making the effort.
     
    CantThink, merylg, MeSci and 2 others like this.
  9. kangaSue

    kangaSue Senior Member

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    Mis-diagnoses do occur between the two. Lems can just be idiopathic and have no involvement with lung cancer, you only get lung cancer with paraneoplastic syndrome, i.e. you have symptoms of cancer but it has not yet materialised somewhere in the body.
    http://www.ncbi.nlm.nih.gov/pubmed/15257511

    Idiopathic LEMS is an example of channelopathies, several of which have been found along with ME/CFS but there's no detemination whether it is of primary cause or secondary factor. It's known that low grade inflammation in any chronic condition can cause channelopathies, the alteration of ion channel function found in autoimmune dysfunction.
    http://phoenixrising.me/research-2/...annelopathy-in-chronic-fatigue-syndrome-mecfs
     

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