The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
Discuss the article on the Forums.

Are there any alternative or new drugs besides Isoniazid for tuberculosis?

Discussion in 'ME/CFS Doctors' started by Peyt, Apr 19, 2017.

  1. Peyt

    Peyt Senior Member

    Messages:
    417
    Likes:
    118
    Hi,
    Does anyone know if there are any alternative or new drugs or therapies besides Isoniazid for tuberculosis?
    Thanks
     
    Jennifer J likes this.
  2. Peyt

    Peyt Senior Member

    Messages:
    417
    Likes:
    118
    Wow, does this mean Isoniazid is still the only choice??
    I was skin tested 32 years ago and was positive for TB although did not have the active symptoms... I was prescribed Isoniazid that I was suppose to take for 9 months. Well soon after 3 weeks I had such violent side effects(sever headaches, and insomnia) that I had to stop...

    32 years later, I still have blood in my mucus daily. I was hoping if I go to my Doctor to discuss this, I could at least ask
    for a new medication or therapy besides Isoniazid. It's said that in 32 years nothing new has been done for this disease. :bang-head:
     
    Jennifer J likes this.
  3. Jonathan Edwards

    Jonathan Edwards "Gibberish"

    Messages:
    5,228
    Likes:
    31,882
    There are at least a dozen different drugs for TB and traditionally treatment has involved using a mixture of 3 of these, according to organism sensitivity or other factors. Isoniazid has often been used as a preventive therapy where latent TB is suspected but overt disease is not present.
     
    Jennifer J and Peyt like this.
  4. Basilico

    Basilico Florida

    Messages:
    827
    Likes:
    1,974
    I just recently learned about andrographis (andrographolide is the main active compound) on another thread that some people here have used to recover from infections more quickly. I'm still in the process of researching it, but it seems to have potential specifically for TB. Might be worth looking into.

    https://www.ncbi.nlm.nih.gov/pubmed/26245695
     
    Peyt likes this.
  5. Peyt

    Peyt Senior Member

    Messages:
    417
    Likes:
    118
    I would call mine a latent version since whenever they did chest x-ray they could not find any activity. So this is why I kinda let it go... To this day, I still don't know if I really have/had TB or its just dry sinuses that cause the blood showing up in the mucus all the time. But I also have Chronic Fatigue.
     
  6. Strawberry

    Strawberry Senior Member

    Messages:
    799
    Likes:
    1,492
    Seattle, WA USA
    Is this common with ME/CFS? I was tested positive 40 years ago?!

    If not the positive skin test, then from the medication? @Jonathan Edwards do you know?
     
  7. Basilico

    Basilico Florida

    Messages:
    827
    Likes:
    1,974


    @Peyt I just recently had to get a blood test to check for any sign of TB before starting an immune suppresant; I'd previously gotten the skin test before, so I was curious as to why my doctor specified that I had to be tested via blood. I found this on Quest Diagnostic's website:

    Clinical Significance
    tuberculosis is a communicable disease caused by infection with M. tuberculosis complex. Infection results in either acute disease or Latent TB Infection (LTBI), a non-communicable asymptomatic condition. The main purpose of diagnosing the latent stage is to consider medical treatment for preventing overt disease. Until recently, the tuberculin skin test was the only available method for diagnosing LTBI. QuantiFERON®-TB gold eliminates false positive skin test due to BCG vaccination and most Non-Tuberculous Mycobacteria (NTM) and is an objective, reproducible qualitative test. There are no side effects or adverse reactions due to patient hypersensitivity, and no "booster effect", whereby the first test induces a false positive response on re-testing. There is no need for follow-up patient visits to obtain test results.
    http://www.questdiagnostics.com/testcenter/BUOrderInfo.action?tc=19453&labCode=SEA

    So while you could have had a Latent infection, it seems like the skin tests were prone to false positives. Might be worthwhile to get the TB gold test to verify what your status actually is.
     
    Jennifer J and Peyt like this.
  8. Peyt

    Peyt Senior Member

    Messages:
    417
    Likes:
    118
    Wow, this is great, thank you so much,
    I will ask my Dr. to order it for me .
     
    Basilico likes this.

See more popular forum discussions.

Share This Page