I'm the guy who has chronic fatigue syndrome symptoms and also responds extremely well to phenibut. Calm-aid seems to be helping a ton, I feel like 60% recovered for the last week, my cognition and mental endurance is much better. I noticed my muscle problems disappear and my jaw/neck/shoulder/leg muscles are no longer tight and imbalanced. Normally my neck leans to the right, and my right leg is twisted outwards a bit. My core usually feels very weak. I normally wouldn't post until like 2 months of testing but I'm going to post anyways, so beware this entire post might be complete shit or the drug's good effects will get full tolerance after 2 weeks. Related research: https://en.wikipedia.org/wiki/Myofascial_trigger_point#Pathophysiology Says trigger points can be caused by excessive acetylcholine release in muscles, causing tightness, reducing blood flow, causing pain and messing with energy dynamics. http://www.sciencedirect.com/science/article/pii/S1043661800906716 Linalool, one of the two main ingrediants in lavender, has an "inhibitory effect on the acetylcholine (ACh) release and on the channel open time in the mouse neuromuscular junction". Also it "demonstrates a local anaesthetic action, either on the voltage or on the receptor-activated channels." Voltage channels are interesting to me because of phenibut being a VDCC inhibitor. Lots of other different mechanisms here: http://www.hindawi.com/journals/ecam/2013/681304/#B50 http://examine.com/supplements/Lavender/ This is a very good list of things. Interestingly lavender reduces canker sore size. I've also had canker sores and once sores in the right side of my mouth after I thoroughly massaged my sore jaw. Perhaps HHV activation has some sort of correlation with an increase in excitatory activity that lavender decreases. Note that phenibut and lavender both seem to decrease my acne quite a bit overnight. I probably have to try out a few different anticonvulsants to narrow down what is actually helping me. Also GABA-a drugs. Maybe the mechanism for my CFS is muscular contraction -> decreased blood flow + decreased digestive system function -> poor energy availability. EDIT: Got tolerance after 6 days. Dammit. It is probably like every other drug I've tried, stops working. EDIT2: Smelling lavender oil still works for some reason ???? nice.