Thanks for your input GlenP and Mr. Kite. I would rather know about the negatives too than go in thinking there weren't many. I am very allergic to niacin, so I wonder if that would be a problem with NADH. I did remember reading that it was a B3 link but am just now realizing if I was allergic to the niacin supplementation than I could also have an adverse reaction to NADH. Hmm? What to do? Anyone have a coin to flip? Thanks for the info, Oerganix!