The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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Anyone on Gaba and Rivotril (Klonopin)?

Discussion in 'General Symptoms' started by Zuriel, Jul 19, 2011.

  1. Zuriel

    Zuriel

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    Australia
    I have started tapering a little off 0.25mg night dose of Rivotril for the past 2 weeks with no side effects. The melatonin spray I'm taking has 2.5mg Gaba, which I suppose helps me maintain 10 hours of sleep.

    Does anyone consume a higher dose of Gaba while going off benzos? Would love to hear your experience. Thanks.
     
  2. Nielk

    Nielk

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    Hi Zuriel,

    Klonopin (which I'm on) increases the amount of Gaba in your brain.
    I don't know about the supplement GABA.
    Logically, it would make sense that it should help with Klonopin withdrawal symptoms as it would fill in the gap of GABA depletion.
    I have no experience doing this and never took GABA supplement. The only possible difficulty that I can think of, is the quantity question. How much GABA to take to compensate.
    I would not try this on my own without a doctor's guidance. You don't want to mess up with your brain.
    Good luck.
     
  3. Wonko

    Wonko Senior Member

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    England
    Unless taken at fairly high doseage GABA suppliments wont pass the blood brain barrier, for me that doseage is about 3g (it's supposed to be 6g for a 'healthy' individual), if it does pass the blood brain barrier the effects can be quite unpleasant and debilitating (at least in my case).

    However I do take GABA regularly, generally under a gram a night as it significantly improves my ability to recover from just being alive, it's not only (or even primarily as far as I know) used in the brain, it down regulates practically all 'neuro'transmitters and allows anything which has been up regulated to recover.

    I can see why it might help with withdrawal but would suspect the melatonin is assisting sleep which is helping more with the withdrawal than a very low dose of GABA.

    I would concur with the above advice, seek a medical opinion before doing anything.
     

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