Does anyone have any experience of or information about using oxygen for ME/CFS? I have severe ME/CFS, and am bedridden (apart from some brief jaunts to the sofa on occasion!). I have bad orthostatic intolerance. My GP has provisionally diagnosed me with POTS, after measuring my pulse and blood pressure after standing for one minute (and watching my feet go purple and me nearly fainting). She hasn't been able to find a local specialist who knows about POTS and could help me, so at the moment I'm not getting any treatment for it. If I sit upright for more than a few minutes I feel as though I'm being gradually suffocated, have pretty dramatic symptoms, and my muscles get progressively weaker until I can't use my limbs. It can take hours to recover, and I feel kind of desperate for air, even when I'm breathing normally. I've read about impaired oxygen delivery to muscle in cfs here: http://www.clinsci.org/cs/097/0603/cs0970603.htm I'm wondering if breathing extra oxygen would help, or whether, if the problem is with getting oxygen from the bloodstream into the muscles, it wouldn't make much difference? I've noticed that some patients (particularly in the US it seems) use oxygen for their ME/CFS. If anyone has any experience of this, has found it helpful or not, please could you let me know? Thanks.