There is a list somewhere on this blog of things people found helped. Rest and pacing was at the top - and appears to be so with any patient survey. I would be very hesitant to do anything that involves exercise, there has been a lot of media attention on the usefulness of graduated exercise etc.which is very confusing. We don't all have the same symptoms, some are able to exercise but generally they are said to have CFS while those who have relapses after exercise as a symptom are said to have ME. For those with ME the treatment perhaps should be different to those with CFS. I could be wrong, but it seemed the Methylation protocol was liked by people but the majority felt it didn't make them much better. There is a lot of discussion on it on this blog which you would find helpful.