I asked my doc to prescribe me this after reading 'Beating Chronic Fatigue' by Kristina Downing Orr. It's a good read but 200 pages of it can be summarised with this one word. I tried the protocol, starting with one quarter of a pill per day, increasing the dose by a quarter pill per week. I had very positive results on week one and four, way beyond my normal fluctuations. I took it for about 2 months before working back down again, but without repeating the previous results. I tried again after 6 months or so, without luck. Then again 6 months after that, but going straight in with half a pill twice per day, and had a very good week, but no more. Has anyone else had a good experience, or even a good lasting experience with this drug?