I have recently experimented with the use of methyl b-2 that seemd to cause improvement for the first two weeks until i woke up one day with severe brain fog and a stiff neck. Brain fog/Derealization/joint pain as well as many other issues have been big issues for me for years, so it took a while for me to pinpoint the source. I then stopped the methyl b-2 and what do you know? those issues subsided significantly(back to my base levels) I then tried to experiment with the methyl b-2 again but starting at a very small dose, ALL symptoms came back full force so i discontinued. Today i went and got some Jarrow methyl b-12 from vitamin shoppe and broke the pill into fours. Once again, all symptoms came back full force and i am currently suffering. I am a little confused as to why even the tiniest amount of methyl would set these symptoms off. I have been reading about methylation for some time now but i seem to be lost in my own journey.