Last week I upped my HC dose from 20 mg to 25 mg and I have been having more anxiety since the increase. Before the increase, anxiety was very well managed. I've been on HC for about 4 months. The increase was due to Nature Throid meds having no effect. I am up to 2 grains of Nature Throid with no increase of energy or really not noticing any difference. Dr thought and I had also read that if there is no effect from thyroid meds then adrenals may not be optimal yet. Why would anxiety increase with an increase of HC? Makes no sense unless the increase is shutting down my own production of cortisol meaning I am actually getting less cortisol overall. If this is the case is this a bad thing? If my body is slowing down production I think that wouldn't be good. I'm afraid I might be setting myself up for a life time of being on HC. Any thoughts?