Relatively speaking the treatment have a good safety profile if the patient is being monitored (standard blood tests): You can pick it up quickly if the patient is getting kidney or liver issues, so if monitored, that's not a problem. If you're worried that the other side of the issue has not been debated, then I suggest that you read through part one of the thread. It has every argument you have brought up. I think we can agree that one size does not fit all. And the decision is at last for the patient and doctor to make together. Personally I would choose to treat rather then not treat. But that's my decision to make, just as it's your decision that you would not do it. I think we all know each other positions... If someone plans to discuss the right-or-not-right topic further, then please check the old thread first. I'd like this thread to remain readable.