one question I am starting to have thinking ahead to when or if PWCs positive for XMRV get treated is this. CFS is thought to be have as a central feature a disturbance in the Central Nervous System. Thus, one might think that the XMRV has penetrated there. But one of the current troubles in treating HIV is that antiretrovirals don't generally penetrate the blood brain barrier very well. So how would these medications (like AZT, for instance) be able to get to cells infected with XMRV in the CNS - which is at the core of CFS?