I think we want to see lab tests showing values before and after treatment to have evidence of abnormalities becoming normalized. Sushi P.S. For perspective, some of the best ME/CFS clinicians and researcher have been studying the pathogenesis of this disease for 18 years or more and still only partly understand it. If you get patients who have been diagnosed through the accepted criteria, such in the International Criteria, they will most likely have lab tests showing abnormalities and many are getting tested periodically to monitor their condition. So, take patients who meet the established criteria, and compare tests before and after treatment...and please post it here!