aquariusgirl
Senior Member
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hi, i suspect i have anemia of chronic disease. I would like to run some blood tests to confirm this. I was thinking ferritin, ZPP, TIBC. Not sure if I need serum iron. Any thoughts? Thanks.
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I think that ZPP is the best test to diagnose anemia of chronic disease because it is a end point control of the whole iron metabolism.
"ZPP is not a simple parameter of iron deficiency but rather
a screening parameter of iron deficient erythropoiesis, surveying
all steps of the iron metabolism from iron uptake to
its utilization. Thus, the ZPP determination can serve as a
kind of “end point control” of the whole iron metabolism,
which detects real iron deficiency as well as derangements of
iron metabolism in chronic inflammatory and neoplastic
disease in sideroblastic disorders, eg, myelodyplasias,
or after lead poisoning"
http://bloodjournal.hematologylibrary.org/content/81/5/1200.full.pdf
Do you have any idea which labs test for hepcidin in the US? My doc has been unable to locate any. Thanks!Hepcidin could also be helpful.
450 euros? OUCH! That's over 500 US dollars.@out2lunch
Black soyabean seed coat extract and Caulis Spatholobi are hepcidin inhibitors, maybe they could help.
Unfortunately I don't know any US hepcidin testing lab, the only one I know is in the Netherlands. They charge you 450 euro's for an iron panel, including hepcidin. The same group is also trialing a new hepcidin inhibitor (lexaptepid).