I spent most of the summer at a membership RV camp out in the foothills Southwest of Denver. In the course of day after day of hard recreation and rebuilding a 336 sq foot deck that was rotting out I met about a dozen people with these various symptoms of FMS and CFS, some diagnosed, some not. Of the ten or so that wanted to try the vitamins and responded, every one of them had a clean and successful startup regardless of which exact symptoms they had because they didn't put their identities in their illnesses or theories. They were willing to suspend disbelief long enough to actually give these things a try as stated and get started, yes with potassium and more Metafolin needed generally on day 3 and approached with a straightforward problem solving attitude. There was nobody taking hundreds of mgs of various b vitamins or glutathione. The one person having terrible "detox" from Cerefolin with NAC was able to reverse that with straight Metafolin with the other 3 of the deadlock quartet. She was feeling better in 1 day, skin lesions half healed in 3 days and all traces gone in a week. None of them had any favorite theories so they didn't alter things, add extras, skip steps or anything else. None of them had a belief system that had them insisting they had to do things. They didn't know "detox" from a hole in the ground. Boy, it was so easy. Reminds me of all those folks back on WRONG DIAGNOSIS that were looking to solve their problems without the precondition that it had to fit their beliefs. There the discussion progressed step by step from initial start up and through each layer. Nobody argued "detox" for the hundredth time and insisted on keeping it year after year. As Rich said some months before his death, 3 months is plenty of time to know if what one is doing works. And that includes EVERYTHING one is doing because even one item, too much or too little or just wrong, can completely prevent healing. It is delicate. So it is quite predictable that a person taking glutathione will NOT succeed in general healing startup and so on. Personally I found that when I learned how to determine that healing has stopped or something is going wrong in a few days or week, progress can be much faster than waiting years. It was indeed a vacation. Nobody kept banging their heads against the stone wall. Of course head banging or not is free will. Have fun. Good health to all.