Hi All,
I have read a considerable amount on this forum since 2010, but this is my first time posting. I am not good at asking for help, but its time I get over that hang-up. I am way overwhelmed these days and was hoping maybe someone here could help me???
I will spare the details, but really quick: I am a 39 y/o male who got sick in 2006 after several years of exceedingly high levels of mental, emotional, spiritual stress. Felt like I got recurrence of mono one morning and its has never gone away...though the immune-ish symptoms are no longer the dominant ones.
I have made several stabs at the active B12 protocol...Apr 2011- Jan 2013, Sep-Oct 2014, and I just started again about 10 days ago. Some background tid-bits
-I "react" to the MB12 (1MG) and Folate (1MG)...major toxic brain fog feeling, mega hang-over feeling leading to swollen glad reaction. On my first attempt ('11-'13) I just got worse and worse until I was sleeping 15-18 hours a day with what felt like an endless redwine hangover without the party. More folate and or B12 did not help...the symptoms did not seem to align with low potassium.
-More recently the start-up reaction (with all cofactors in place before starting), I had clear feelings of increased tingling, throbbing, burning etc (it was already starting after 2 months on just the co-factors) at sign of an old nerve entrapment injury 15 years ago. This along with slightly increased whine/ring in ears (like brain is buzzed up a bit...similar to when I started Effexor years back) indicated to me that this is start-up. Or might it just be inflammation due to increased excitotoxicity from sulfur/ammonia issues?
-I am beginning to get some of the symptoms I have when I tried this a few years ago (toxic feeling in morning, tired/wired). Given my SNPs (hopefuly they will show in my sig line) and a hair test I had done for Nutritional Balancing Program where I was told I am a fast metabolizer with protein catabolism (body is using its own tissue for protein metabolism), I am worried that I may be ammonia toxic??
-Amino Acids Analysis does not indicate high taurine
Questions
-My SNPs dont seem to be too bad considering others I have seen on the forums...or not? How does one know when B12/methylation etc is just not the issue or I need to keep cracking at it and working more methodically and patiently?
-Does ANY reaction to B12 (even when most of symptoms are a toxic vice energizing feeling) suggest I need help here?
-How does one know when we must increase folates doses to get out of deficiency or when its just a matter of healing not complete. For example, Freddd said it took several years to heal his gut, but gut issues are also a folate deficiency symptom? Likewise...increased anxiety is a start-up symptom but also a low potassium/folate symptom? When to keep titrating or when to hold? or when to say this is not ones healing path....?
Current dose of DQ (plus all cofactors)
-1,500mcg for Folate (titrated up since 6 Feb. No noticable reaction)
-1,500mcg MB12 (titrated up since 9 Feb. More tingling and throbbing in shins and top of feet which had already begun when I started cofactors weeks earlier. Plus bouts of much brain fog and mental fatigue/slowing)
-2000mcg ADB12 (titrated up since 16 Feb. Feelings a little “buzzy” in head...like too much thyroid med...less deep sleep and sweats during night)
-855mg of Carnitine (started 17 Feb...more buzzy in head and caffeinate feeling)
Ok...I fear this is too long already and I have many more questions. ANY help would be deeply appreciated…
Kindly
Michael
ahmo, freddd, caledonia, dbkita
I have read a considerable amount on this forum since 2010, but this is my first time posting. I am not good at asking for help, but its time I get over that hang-up. I am way overwhelmed these days and was hoping maybe someone here could help me???
I will spare the details, but really quick: I am a 39 y/o male who got sick in 2006 after several years of exceedingly high levels of mental, emotional, spiritual stress. Felt like I got recurrence of mono one morning and its has never gone away...though the immune-ish symptoms are no longer the dominant ones.
I have made several stabs at the active B12 protocol...Apr 2011- Jan 2013, Sep-Oct 2014, and I just started again about 10 days ago. Some background tid-bits
-I "react" to the MB12 (1MG) and Folate (1MG)...major toxic brain fog feeling, mega hang-over feeling leading to swollen glad reaction. On my first attempt ('11-'13) I just got worse and worse until I was sleeping 15-18 hours a day with what felt like an endless redwine hangover without the party. More folate and or B12 did not help...the symptoms did not seem to align with low potassium.
-More recently the start-up reaction (with all cofactors in place before starting), I had clear feelings of increased tingling, throbbing, burning etc (it was already starting after 2 months on just the co-factors) at sign of an old nerve entrapment injury 15 years ago. This along with slightly increased whine/ring in ears (like brain is buzzed up a bit...similar to when I started Effexor years back) indicated to me that this is start-up. Or might it just be inflammation due to increased excitotoxicity from sulfur/ammonia issues?
-I am beginning to get some of the symptoms I have when I tried this a few years ago (toxic feeling in morning, tired/wired). Given my SNPs (hopefuly they will show in my sig line) and a hair test I had done for Nutritional Balancing Program where I was told I am a fast metabolizer with protein catabolism (body is using its own tissue for protein metabolism), I am worried that I may be ammonia toxic??
-Amino Acids Analysis does not indicate high taurine
Questions
-My SNPs dont seem to be too bad considering others I have seen on the forums...or not? How does one know when B12/methylation etc is just not the issue or I need to keep cracking at it and working more methodically and patiently?
-Does ANY reaction to B12 (even when most of symptoms are a toxic vice energizing feeling) suggest I need help here?
-How does one know when we must increase folates doses to get out of deficiency or when its just a matter of healing not complete. For example, Freddd said it took several years to heal his gut, but gut issues are also a folate deficiency symptom? Likewise...increased anxiety is a start-up symptom but also a low potassium/folate symptom? When to keep titrating or when to hold? or when to say this is not ones healing path....?
Current dose of DQ (plus all cofactors)
-1,500mcg for Folate (titrated up since 6 Feb. No noticable reaction)
-1,500mcg MB12 (titrated up since 9 Feb. More tingling and throbbing in shins and top of feet which had already begun when I started cofactors weeks earlier. Plus bouts of much brain fog and mental fatigue/slowing)
-2000mcg ADB12 (titrated up since 16 Feb. Feelings a little “buzzy” in head...like too much thyroid med...less deep sleep and sweats during night)
-855mg of Carnitine (started 17 Feb...more buzzy in head and caffeinate feeling)
Ok...I fear this is too long already and I have many more questions. ANY help would be deeply appreciated…
Kindly
Michael
ahmo, freddd, caledonia, dbkita