We are in for a paradigm shift in testing. Abbott a big company in pharma and medical equipment have made an just amazing broad-based molecular pathogen identification system. It can detect over 1000 pathogens in one test (they run it through a database) its an combination of an PCR and electrospray ionization mass spectrometry https://iridica.abbott.com/technology.html (thats means it uses the best tests around to identify phatogens not immuneresponse). It can test for bacteria, virus and candida and you dont have to what know you are searching for. Its called Iridica and its already in use in Karolinska stockholm. To have a study with this equipment on ME patients would be something.