Hi All, Does anyone know if ALA increases Dopamine? I have COMT +/+ and generally do very poorly with supplements like Tyrosine (very bad headaches) and even SAMe... so I also noticed when I take Alpha Lipoic Acid (I have tried at least 3 brands) I get a headache after a couple of days... If I manage to stay on it for a few days though I also notice the aches and pains in my body is gone and my sugar cravings reduce so I am trying to figure out if the headaches have to do with excess dopamine or something else.... The reason I am wondering about dopamine is because I generally get headaches from 2 types of supplements, one which increases dopamine or saratonin (ex: Tyrosine, St. John, SAMe, ......) and one that the bacteria in my gut feeds from (such as Choline) and then bacteria dumps their waste in the blood stream and causes me headaches which my Chinese Medicine Doc likes to call liver toxicity headaches....... I have found a ALA cream that I am considering buying as long as ALA does not increase dopamine,... the cream helps me get around the bad bacteria problem that I have in my gut which causes the 2nd type of headaches I mentioned.. ( I have SIBO) Thanks for your comments in advance.