I recently increased my methylfolate from 200 mcg to 800 mcg. It was going really well for about a week. My energy, focusing, and sleeping all improved. I'm not sure whether it helped my muscles or not since I recently had an improvement in this area by getting acupuncture treatments (before starting the increased methyfolate). For the past few days, my throat has felt strangely constricted, especially when I lay down. This feeling has increased, and is bothering me more each day....so I got online today and found that one of the allergic reactions to methylfolate is a swollen throat. Looking back to my smaller doses, I now realize that I commented to my husband that my breathing felt "different" while we were hiking last month. So, what's a person to do when the methylfolate actually seems to be helping, but now must discontinue due to this allergic reaction?