Waverunner. When it comes to the enterovirus hypothesis, is there a specific virus in the group that's a suspect, or is it the group as a whole. Do you or alex3619 know of a study that highly indicates that such mechanisms may be involved? I totally agree with your last paragraph. IMO, research such as the horrible Tuskegee syphilis experiment have contributed strongly to shifting the ethics guidelines from "everything is OK" to "almost nothing is OK". When the pros clearly outweigh the cons, then permission should naturally be granted - but I know many valid research projects which have been killed in the cradle by an ethics committee - even totally harmless research regarding analysis of blood samples.