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Alcohol Tolerance Poll

Discussion in 'Hypersensitivity and Intolerance' started by Cort, Oct 7, 2010.

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The Alcohol Tolerance Poll

  1. My tolerance of alcohol shifted after I got ME/CFS

    184 vote(s)
    46.6%
  2. My tolerance of alcohol did not shift after I got ME/CFS

    36 vote(s)
    9.1%
  3. After ME/CFS I don't do well with even small amounts of alcohol

    248 vote(s)
    62.8%
  4. After ME/CFS I do OK with small amounts of alcohol but can't tolerate moderate to large amounts

    67 vote(s)
    17.0%
  5. LOL I can actually drink more alcohol now without it effecting me!

    19 vote(s)
    4.8%
Multiple votes are allowed.
  1. gregh286

    gregh286 Senior Member

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    Londonderry, Northern Ireland.
    Funny i tend to improve for a few days after a binge.
    Have'nt worked it out yet but i think it might be suppressing my immune system (th2 specifically) temporarily, giving me respite for a while.
    Bizarre.
     
    sarah darwins likes this.
  2. sarah darwins

    sarah darwins I told you I was ill

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    Ditto. Not that I'd suggest it as a therapy! :)
     
  3. MeSci

    MeSci ME/CFS since 1995; activity level 6?

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    Yes, I did a bit of searching, and got as far as buying some fizzy water, but couldn't find the flavourings. I tried various online sources and my local homebrew shop - no good. So tried various other things to go with the gin, and have settled for orange juice. During my searches I was very puzzled to find that it seemed impossible to buy simple, unsweetened, organic raspberry juice, which I thought might be a good candidate mixer for gin.

    Wild raspberries grow very well round here, so I may start encouraging them again - in containers, as they spread like crazy in the ground!
     
  4. lookinglass

    lookinglass Senior Member

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    Only just come across this thread. I have always had alcohol intolerance. Hate it. Wine, every kind, smells like petrol and tastes like battery acid. Whisky and all other hard liquor made me vomit, gave me migraines and pains down my left arm. No change when I got M.E. 8 years ago.
     
    PhoenixDown likes this.
  5. SB_1108

    SB_1108 Senior Member

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    There was a study being done recently about alcohol intolerance in ME/CFS. Does anyone remember who was conducting the study? The results should be coming out soon I believe?
     
  6. sregan

    sregan Senior Member

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    Southeast
  7. PallasKat

    PallasKat

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    This is really interesting to me too because, since I have had CFS/ME I have been able to drink very small amounts of vodka once in a while. I found this out after a LOT of trial and a LOT more error.

    AND, hard cider is MURDER. Before even finishing a bottle of hard cider, my body starts to lock up, I get a terrible headache and I feel like I am about to come down with the worst flu imaginable.

    Thank you, @Sean for explaining why this is! P-Kat:cat:
     
    sarah darwins and Sean like this.
  8. osisposis

    osisposis Senior Member

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    lols, how do you vote? sence I got ill I cant tolerate any alcohol at all, and cant even tolerate being in a room with people drinking, the smell itself use to cause hypersensitivity reactions, still does but not as obvious as it was when I first got ill and for many years, last time I was tempted by a froend to try one drink , I started halausenating (sorry spelling) and about caused a reck because I grabed the stearing whell because I thought he was driving in oncoming traffic, needless to say no one has tried to get me to drink sence. does anyone else have MCS/REACTIONS just from the smell? I also have anaphylaxis and anaphylatoid reactions and got sick from exposure in a water damaged high moisture moldy home, I am highly allergic to mold mixes and have anaphylaxis to mold extracts and very reactive to voc's ,
     
    Last edited: Aug 13, 2016
  9. Thinktank

    Thinktank Senior Member

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    I now tolerate alcohol better than a few years ago, but nowhere as good as pre-lyme/ME.
    Funny thing though is that alcohol doesn't give me a buzz anymore, it only intensifies the brainfog / drunk feeling that i already live with 24/7.
     
  10. osisposis

    osisposis Senior Member

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  11. osisposis

    osisposis Senior Member

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    IN OTHER WORDS, reactive airways and beyond.

    Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia.

    https://www.ncbi.nlm.nih.gov/pubmed/10995440

    Purinergic signalling and immune cells.

    https://www.ncbi.nlm.nih.gov/pubmed/25352330

    Purinergic Signal. 2016 Jun;12(2):235-46. doi: 10.1007/s11302-016-9497-4. Epub 2016 Feb 24.
    P2X7 receptors induce degranulation in human mast cells.
    Mast cells play important roles in host defence against pathogens, as well as being a key effector cell in diseases with an allergic basis such as asthma and an increasing list of other chronic inflammatory conditions. Mast cells initiate immune responses through the release of newly synthesised eicosanoids and the secretion of pre-formed mediators such as histamine which they store in specialised granules. Calcium plays a key role in regulating both the synthesis and secretion of mast-cell-derived mediators, with influx across the membrane, in particular, being necessary for degranulation. This raises the possibility that calcium influx through P2X receptors may lead to antigen-independent secretion of histamine and other granule-derived mediators from human mast cells. Here we show that activation of P2X7 receptors with both ATP and BzATP induces robust calcium rises in human mast cells and triggers their degranulation; both effects are blocked by the P2X7 antagonist AZ11645373, or the removal of calcium from the extracellular medium. Activation of P2X1 receptors with ╬▒╬▓meATP also induces calcium influx in human mast cells, which is significantly reduced by both PPADS and NF 449. P2X1 receptor activation, however, does not trigger degranulation. The results indicate that P2X7 receptors may play a significant role in contributing to the unwanted activation of mast cells in chronic inflammatory conditions where extracellular ATP levels are elevated.
    ATP; Degranulation; Mast cells; P2X

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854833/
     
  12. roller

    roller wiggle jiggle

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    i tried ethanol (100% alcohol, they say) from the pharmacy.
    about 120ml before "bedtime".
    3 times so far, up to 7 days apart.

    i had quite some hopes, but nothing.

    i feel drunk for 2 or 3 days after, particularly when walking.
    nausea like motion sickness.
     
  13. SueJohnPat

    SueJohnPat Sue

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    Medford NJ
    I stick to vodka. Wine I can tolerate one glass but that's about it.
    A few years alcohol repelled me did not drink at all. Feeling much better able to tolerate a drink. Vodka has no after effects for me and sometimes will get rid of fibro pain. I never drink more than 2 drinks anymore

    For a few years I did not drink at all. have recovered to some extent. I don't push it, but I am more active now and sometimes get fibromyalgia pain at night. I have tramadol but if I take it at night it keeps me awake so I have a drink.
    Once a few years ago I was at a play in center city. I forgot my pain pills. Pain was bad could not enjoy the play. At intermission had a shot of vodka at the bar. Pain gone able to watch play.
     
    *GG*, MeSci and sarah darwins like this.
  14. Matthew Jones

    Matthew Jones Senior Member

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    I had a bad crash after playing football for 10 minutes Saturday. The next day (yesterday) I felt like I had been pummeled all over my body. I drank some beer and found it made me feel okish again, I could listen to music from my bed and generally be in an upbeat mood. I drank 3 pints and in the end the day was not too bad.

    The next day (today) I had recovered mostly from the PEM from the football but found it hard not to have a drink. I drank 4 beers.

    Its such a dismal situation, i hate just wasting my life in bed, if I slowly consume alcohol I feel positive and cheerful and have a bit more energy. It turns a crap day into a fun day. Its a bit worrying as i'm finding it very addictive. Even though I dont usually drink, once you get used to having that relief its hard to take it away. I'll try and stay away from it tomorrow but I can't make any promises. I mean, it genuinely improves my quality of life. But long term i know its bad to rely on it.

    I would take pain killers instead if I had them but I don't have any. I don't know what to do instead. Its drink and feel alright or lie in bed feeling ill.

    For the first few years of illness I was completely intolerant to alchocohol. I didnt drink anything for 5 years as a result. But then I became tolerant to it again and finding it hard to cope without it. Not a good situation.
     
    *GG* likes this.
  15. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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    Hey Matthew, i`m in the same boat.

    I strongly need to warn you about drinking more than 1-2 days a week though, you might not end up an alcoholic (as that seems to be of somewhat genetic nature), but you will inevitably end up standing at the crossroads realizing you are drinking too much, with all the guilt and self loathing that contains. Try finding something else most days in the week, that lightens you up, and keep the alcohol for the weekends :) Using ME/CFS as an "excuse" is very dangerous, iv`e been there some months after a breakup, and I saw a lot of lost souls in the pubs.. Everyone had some excuse..
     
    Matthew Jones likes this.
  16. NelliePledge

    NelliePledge plodder

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    I only normally have one small glass of wine (Provence rose by choice) if socialising with friends/family I go for weeks without having a drink these days. But I made the mistake on Saturday of 3 glasses and had a terrible night slept only in the early hours after my heart stopped racing. I will not be doing that again

    I wouldn't recommend vodka as "better" than other types of alcohol. I've known two people who had drinking issues and both used vodka as their drug of choice. The fact that you might have fewer negative effects for the amount of alcohol isn't a good thing if it means you consume more. Alcohol is a terrible drug if it had only just been invented it would be a Class A due to the level of harm. I've seen my parent struggle with the physical addiction and die of the ravages of alcoholic liver disease.
     
    MeSci likes this.
  17. gregh286

    gregh286 Senior Member

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    Londonderry, Northern Ireland.
    I say whatever makes you feel better with CFS take it.
    It's a brutal enough illness without skipping factors that improve you.
    Granted you need to be able to control your intake.
     
  18. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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    I`m talking about alcohol abuse, which it is after a certain treshold is reached.
     
  19. Matthew Jones

    Matthew Jones Senior Member

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    Thanks for the advice. As frustrating as it is to have something that eases the CFS right there available I don't think the side effects which would build up would be worth it so I'll keep it to a minimum. Not feeling too bad today anyway actually luckily, though too tired to go anywhere.
     
    Marky90 likes this.
  20. Basilico

    Basilico Florida

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    My husband is a professional distiller (and lately has gotten into home brewing wine/beer/mead). When he's distilling, he applies a very conservative cut at the beginning to remove any traces of methanol. When he's fermenting, he disinfects things with boiling water, never the chemicals that are frequently recommended.

    We've both noticed that if we drink something he's distilled or fermented, we don't have negative effects like headaches. However, we do often get headaches from anything that we drink that was commercially made. So while I could drink several glasses of his mead and feel fine, we will both often get a headache if we drink a bottle of beer or a glass of wine that was commercially produced.

    We originally though it was the histamines that were a problem, since it used to be that fermented beverages bothered us while spirits didn't, now it doesn't seem to matter whether it's something distilled or fermented, it just matters whether he made it or not :)
     

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