The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
Simon McGrath concludes his blog about the remarkable Prof George Davey Smith's smart ideas for understanding diseases, which may soon be applied to ME/CFS.
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ALAD rs8177822 anyone?

Discussion in 'Genetic Testing and SNPs' started by Kimsie, Nov 7, 2014.

  1. Kimsie

    Kimsie Senior Member

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    I have noted that at least one of my sons and I both have the GT version of the rs8177822 snp. It looks like not more than about 5% of the population have this, and it looks as if no one or very few are homogeneous (TT). GG is the wild type, which appears to be 95% of the population.

    This gene is for the enzyme which catalyses the second step in the pathway to make heme. This enzyme is especially vulnerable to lead.

    Do any of you have this mutation?
     
  2. Valentijn

    Valentijn Senior Member

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    @Kimsie - out of 31 ME patients I have full data for, 2 have GT. 3 out of 31 controls also have GT.
     
  3. Kimsie

    Kimsie Senior Member

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    So it doesn't look very significant to me. That's what I wanted to know. Thanks!
     

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