I just ran across the definition of this word by googling restlessness and neurotransmitters. I have a near-constant uneasy feeling marked by a sensation (malaise, nervous sensation) in my torso and shoulder areas and subsequent uneasiness/nausea. During the day, I often can't rest, and on my worst days, I count the minutes until evening time when I usually feel better. Many times, I can sleep (even though I wake up periodically) but then when I wake up in the morning, I can hardly lay there peacefully because of the restlessness. The severity varies, but right now, it's present every day. And it's debilitating. This was not initiated by any SSRI or similar drug. I'm on many supplements now, but I think this feeling was the original sensation that took me down the road of CFS, adrenal dysfunction, etc. and the subsequent treatments. Is anyone knowledgeable about this topic? Is it caused by levels of dopamine?