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Agomelatine but not melatonin improves fatigue perception: a longitudinal proof-of-concept study

Discussion in 'Latest ME/CFS Research' started by MikeJackmin, Mar 1, 2014.

  1. Beyond

    Beyond Juice Me Up, Scotty!!!

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    Murcia, Spain
    I am going to start Amitryptiline this night. Yeah, apparently it causes commonly heartbeat problems from what I have been reading. Heart problems are pretty scary, have only experienced them once.

    Other candidates are: Mirtazapine, Clonidine, Ritanserin, maybe Quetiapine.
     
  2. snowathlete

    snowathlete

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    UK
    good luck. be warned: you will feel like s**t for at least a week when you start this drug. It does pass - at least it did for me.
     
  3. NotThisGuy

    NotThisGuy Senior Member

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    Germany
    Any news to this drug?
     
  4. frederic83

    frederic83 Senior Member

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    France
    I'm going to try agomelatine soon.
     
  5. frederic83

    frederic83 Senior Member

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    France
    After a few days on it, I'm a bit more tired 1 hour after the dose but I don't sleep. Then the sleepiness vanishes and I'm wide awake, as usual. I wait a few hours to see if something else happens. Then it is 6 am and I finally take my melatonine otherwise I don't sleep. I will try it for a week or so, I don't think it is that powerful.
     

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