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Aescin - a most unusual response

Discussion in 'General Treatment' started by ramakentesh, Mar 22, 2012.

  1. ramakentesh

    ramakentesh Senior Member

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    Recently my doctor ok'd the use of Horse Chestnut or aescin to combat dizziness from POTS. I took a minute dose and my BP went up to 197/106!
    ive been thinking about this hypertensive response to a minute dosage of this herbal preparation.
    it is reputed to act on serotonin receptors specific to the veins and via release of prostglandulins. The former has been found to be abnormal in CFS and through my own experience (supersensitivity to mild herbal SSRIs which suggested upregulated 5-HTa2 receptors at a guess) and the later has been implicated at least in a talk by Vanderbilt in the etiology of POTS. Interesting...
    Low peripheral serotonin activity causing upregulation of serotonic receptors in the vasculature?
     
    xrayspex likes this.
  2. xrayspex

    xrayspex Senior Member

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    u.s.a.
    I was searching horse chestnut because I get Intracranial hypertension (ICH) from time to time esp if mess up my neck--and lying down can increase pressure--I have thought about trying diamox but meds and me don't usually agree
    horse chestnut was recommended in the comment section of a blog on ICH as a natural alternative to diamox to lower pressure pain so that is quite paradoxical what happened to you

    http://permanentheadache.blogspot.com/2009/09/day-260-intracranial-hypertension.html

    https://www.drweil.com/vitamins-supplements-herbs/herbs/horse-chestnut/
     

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