The Real ME: A Stock Photography Resource for the Media
We’ve all seen them in the news stories about ME/CFS: the guy in a suit at the office, yawning; the beautiful woman sitting at her desk with her immaculate make-up and elegantly coiffed hair, hand to her head and looking slightly pained.
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Aescin - a most unusual response

Discussion in 'General Treatment' started by ramakentesh, Mar 22, 2012.

  1. ramakentesh

    ramakentesh Senior Member

    Recently my doctor ok'd the use of Horse Chestnut or aescin to combat dizziness from POTS. I took a minute dose and my BP went up to 197/106!
    ive been thinking about this hypertensive response to a minute dosage of this herbal preparation.
    it is reputed to act on serotonin receptors specific to the veins and via release of prostglandulins. The former has been found to be abnormal in CFS and through my own experience (supersensitivity to mild herbal SSRIs which suggested upregulated 5-HTa2 receptors at a guess) and the later has been implicated at least in a talk by Vanderbilt in the etiology of POTS. Interesting...
    Low peripheral serotonin activity causing upregulation of serotonic receptors in the vasculature?

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