hi everyone, (i posted this on prohealth too but thought i'd try here as well, since my registration was just approved.) i'm new to the board but have been silently reading for awhile. i have chronic lyme and coinfections, as well as a diagnosis of CFS. anyway, let me cut right to my question: i don't have insurance or any disposable income so haven't been able to afford genetic or MTHFR testing. however, my ND put me on one folapro/day (800 mcg) regardless, because i muscle tested well for it. i'm also taking sublingual hydroxyb12 and phosphatidyl serine, along with lots of other supportive herbs and supplements and a few antimicrobials targeted at the chronic infections. anyhow, i started with 1/2 tablet for a few days, began feeling strange so stopped taking the folapro for about a week, started again with 1/3 tablet, then a couple days after that was slammed with intense brain fog, run-over-by-a-truck fatigue, sleepiness, a complete and utter feeling of sickness - i was pretty much unable to move or think. needless to say i stopped the folapro again, didn't take it for a couple weeks. two days ago i restarted at a tiny crumb - i ground up the pill in a mortar and pestle and plucked a crumb from the white mess - and again, after two days i am down for the count with all the same symptoms as before. this time they're slightly less intense, but only slightly, and still debilitating. so, my symptoms from even a tiny crumb of folapro include excessive sleepiness, brain fogginess, feeling totally out of it, headache, and just kind-of feeling sick all over, like my body is working something out in an intense way. it's mostly a terrible feeling, but some small seed of it feels productive/healing. however, it isn't compatible with living/working/taking care of myself/being coherent/etc; i live alone and am solely responsible for my care and the care of my two cats, and i need to be able to work part-time. this illness nearly killed me in 2005 - i was bedridden and slowly dying for a year - and since then i've been up and down, but never, knock wood, as sick as i was when it first hit so intensely. and i refuse to go back there. i'm definitely still ill, but am somewhat functional, more functional than many folks who've been able to tolerate much, much higher doses of folapro with little to no additional problems. this has me confused. does anyone have any insight as to why a tiny crumb of folapro affects me in such a profound and incapacitating way? also, i've been reading that i should avoid folic acid while taking methylfolate. my multi has a small amount of folic acid in it - i take alive multivitamin - does anyone know of a good multi that doesn't contain folic acid? sorry for the jumbled post, and thank you in advance for any thoughts!