The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
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Adrenaline rush from MCAS?

Discussion in 'Mast Cell Disorders/Mastocytosis' started by Misfit Toy, Sep 21, 2017.

  1. Thinktank

    Thinktank Senior Member

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    I feel there's a connection between certain pro-inflammatory substances like histamine and a rise in adrenalin / noradrenalin.

    Whenever i take a H1 inhibitor during an "hyperadrenergic" episode it calms me down and reduces inflammation.
    When i take a beta blocker it does calm me down but the inflammation stays.
    Using a beta2 agonist reduces my allergic / mcas symptoms.

    So... antagonizing H1 receptors = decrease in adrenalin / noradrenalin? With less histamine binding to its receptors the body senses less need for adrenalin/noradrenalin.
    The same goes for cortisol, low cortisol drives high adrenalin/noradrenalin.
    Please correct me if i'm wrong.
     
  2. ryan31337

    ryan31337 Senior Member

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    Gingergrrl and Thinktank like this.

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