I've read people refer to pain or discomfort in their adrenal area. I was just wondering if this was a genuine phenomenon. Sometimes I experience a dull-ish ache or discomfort in my back, a few inches above my buttocks. I've been starting up methylation and am having 'detox' (i.e. flu-like) symptoms, with a return of the pain. So I've been wondering if the 'adrenal pain' is a sign we need to ease up ..