I started on the modulating Adrenal Cortex Extract over the last week or so. I started with one drop at noon. My noon cortisol is really high, causing anxiety. The drop made me fuzzy for several hours. This has faded out the longer I take it. It's been very helpful for the anxiety, I would say about 80% resolved. I've worked up to 3 drops at noon, increasing every 3-4 days. The goal is 4 drops at noon, as long as it's tolerated. Then I will start the same process at 3pm, then eventually the same in the morning. However, I'm still sleeping til noon, so I'm not sure what I'll do about the morning slot right now. I'm hoping my sleep cycle will resolve itself by the time I get to that point.