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Adolescent CFS: Prevalence, Incidence, and Morbidity

Discussion in 'Latest ME/CFS Research' started by oceanblue, May 25, 2011.

  1. oceanblue

    oceanblue Senior Member

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    Adolescent Chronic Fatigue Syndrome: Prevalence, Incidence, and Morbidity, 2011
    Sanne L. Nijhof, Kimberley Maijer, Gijs Bleijenberg, Cuno S. P. M. Uiterwaal, Jan L. L. Kimpen, Elise M. van de Putte

    Abstract:
    OBJECTIVE: To determine nationwide general practitioner (GP)-diagnosed prevalence and pediatriciandiagnosed incidence rates of adolescent chronic fatigue syndrome (CFS), and to assess CFS morbidity.

    DESIGN AND SETTING: We collected data from a cross-sectional national sample among GPs and prospective registration of new patients with CFS in all pediatric hospital departments in the Netherlands.

    PATIENTS AND METHODS: Study participants were adolescents aged 10 to 18 years. A representative sample of GPs completed questionnaires on the prevalence of CFS in their adolescent patients. Pediatric hospital departments prospectively reported new cases of CFS in adolescent patients. For every new reported case, a questionnaire was sent to the reporting pediatrician and the reported patient to assess CFS morbidity. Prevalence was estimated through the data from GP questionnaires and incidence was estimated on the basis of cases newly reported by pediatricians from January to December 2008.

    RESULTS: Prevalence was calculated as 111 per 100 000 adolescents and incidence as 12 per 100 000 adolescents per year. Of newly reported patients with CFS, 91% scored at or above cutoff points for severe fatigue and 93% at or above the cutoff points for physical impairment. Forty-five percent of patients with CFS reported >50% school absence during the previous 6 months.

    CONCLUSIONS: Clinically diagnosed incidence and prevalence rates show that adolescent CFS is uncommon compared with chronic fatigue. The primary adverse impact of CFS is extreme disability associated with considerable school absence.

    Found this in Chronic Fatigue Syndrome Research Today' which looks like an agregated list, but handy all the same
     
  2. Snow Leopard

    Snow Leopard Senior Member

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    This tends to suggest that such adolescents don't get better, at least while they are adolescent.
     
  3. oceanblue

    oceanblue Senior Member

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    Neat point, though the confidence interval is probably pretty wide for the incidence figure.
     
  4. Sean

    Sean Senior Member

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    Presumably the authors will argue that is the natural course outcome, and does not necessarily apply to 'treated' patients.
     

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