Does anyone have experience of using adensosine monophosphate as a sleep-aid? I've had serious sleeping problems for the past 20 years and I've tried just about everything. Use ambien (zolpidiem) regularly to get to sleep but wake up 4 hours later (usually between 2-4am) and cannot go back to sleep. No anxiety. Just can't sleep. I have ME and a demanding daily schedule with a half-time job and two young children, and I am desperate to get more than my regular 4-5 hours/night. I would be grateful for ideas....!
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Adenosine monophosphate as a sleep-aid?
- Thread starter Moshi
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*GG*
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Would think you have tried Remeron, right?
GG
GG
@ggingues - Thanks! Remeron = Mirtazapin, certainly rings a bell, must have looked into that one earlier. I will research it, even though I have a dislike for SSRI's that I was able to quit many years ago. I'm certainly not depressed, but the chronic insomnia is not exactly making me joyful either. 
I percieve my problem as an early surge in cortisol and/or adrenaline, beginning as early as around 1-2am. I have tried, L-Theanine, GABA, Lithium Orotate, and Phospatidyl Serine (i.e. Seriphos) before bed but they do not really seem to help much. Sometimes I have considered trying a higher dose of PS, but a little wary it will lower cortisol during daytime, as it is already low.
Any other ideas, anyone?
I percieve my problem as an early surge in cortisol and/or adrenaline, beginning as early as around 1-2am. I have tried, L-Theanine, GABA, Lithium Orotate, and Phospatidyl Serine (i.e. Seriphos) before bed but they do not really seem to help much. Sometimes I have considered trying a higher dose of PS, but a little wary it will lower cortisol during daytime, as it is already low.
Any other ideas, anyone?
*GG*
senior member
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- 6,389
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- Concord, NH
@ggingues - Thanks! Remeron = Mirtazapin, certainly rings a bell, must have looked into that one earlier. I will research it, even though I have a dislike for SSRI's that I was able to quit many years ago. I'm certainly not depressed, but the chronic insomnia is not exactly making me joyful either.
I percieve my problem as an early surge in cortisol and/or adrenaline, beginning as early as around 1-2am. I have tried, L-Theanine, GABA, Lithium Orotate, and Phospatidyl Serine (i.e. Seriphos) before bed but they do not really seem to help much. Sometimes I have considered trying a higher dose of PS, but a little wary it will lower cortisol during daytime, as it is already low.
Any other ideas, anyone?
I take it for sleep, not typically depressed, been working for me since 2009!
GG
heapsreal
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Ambien is really only a goid sleep initiator, i generally add an antihistamine like doxylamine or diphenhydramine to help keep me asleep. Phenergan is another good sleep sustainer .
minkeygirl
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I always wake up in the middle of the night. Usually around 3 am
What works for me with right feeling drugged is any of the following: Passion flower, suntheanine, trazodone, and tizanidine
I find since what ever I took to get me to sleep, Ambien and antihistamines, is still in my system to I don't need anything huge to knock me out like I do when I first try to sleep.
What works for me with right feeling drugged is any of the following: Passion flower, suntheanine, trazodone, and tizanidine
I find since what ever I took to get me to sleep, Ambien and antihistamines, is still in my system to I don't need anything huge to knock me out like I do when I first try to sleep.
@ggingues - my sincere congratulations! Glad you found something that's working for you! Insomnia is a killer. @satori , thanks for the tip but I am never allowed to sleep in, even if I was able to @heapsreal - been using Ambien for 15+ years and yes, it works. 15-20mgs of zolpidiem will almost always send me to sleep....however, it wears off after 3 or so hours, and then I cannot repeat the dose, it would make me even more groggy/foggy in the morning. Will look into anti-histamines, and Phenergan, thanks! @minkeygirl - thanks, I remember taking trazodone when I lived in the US, worked a charm, loved it however, it is like valium right? Old-school benzo...or?
Lot of things to look into here, thanks everyone!
@heapsreal - been using Ambien for 15+ years and yes, it works. 15-20mgs of zolpidiem will almost always send me to sleep....however, it wears off after 3 or so hours, and then I cannot repeat the dose, it would make me even more groggy/foggy in the morning. Will look into anti-histamines, and Phenergan, thanks! @minkeygirl - thanks, I remember taking trazodone when I lived in the US, worked a charm, loved it however, it is like valium right? Old-school benzo...or?Lot of things to look into here, thanks everyone!
minkeygirl
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@Moshi it's an old tricyclic.
@minkeygirl - OK, Thanks! @heapsreal - found I actually have Phenergan at home (sold as "Lergigan Mite" in Sweden), it didn't have much of an effect on me before, but I could easily give it another try.
heapsreal
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In a combo it may help you stay asleep. I find Phenergan on its own doesnt do much.
minkeygirl
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@Moshi @heapsreal got me into the combo routine and it makes a huge difference. Things that don't work on their own work great when combined with other things. It's all about layering stuff for maximum effect.
There are some nights when nothing works but for the most part for me, this is the way to go.
There are some nights when nothing works but for the most part for me, this is the way to go.
@heapsreal @minkeygirl - sure enough, when I woke up at 01:30 last night I tried a combo of 5mg zolpidiem+Prometazin and it helped me sleep, and go back to sleep after my youngest woke me 2hrs later combos seem to fix the problem! Thanks for the idea!
minkeygirl
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@Moshi Try to make sure you don't take the same combo every night to avoid tolerance.
This morning I woke at 3:30 and took 2 mgs tizanadine and slept a few more hours. I have good luck with OTC stuff for my middle of the night wakings. I can't take anything that lasts too long because no matter what I usually wake by 7. If I don't have time to sleep it off I'm drugged the entire next day.
This morning I woke at 3:30 and took 2 mgs tizanadine and slept a few more hours. I have good luck with OTC stuff for my middle of the night wakings. I can't take anything that lasts too long because no matter what I usually wake by 7. If I don't have time to sleep it off I'm drugged the entire next day.
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Please tell me where you buy Phosphatidylserine powder ???
I read your posts already half a year. Please help me solve my problem (((I have high levels of cortisol for a year. I am 23 years .I from Ukraine. Please leave me your contact my email so that I can contact you.
My email 7685858 at gmail dot com
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