Yep, typo! Sheesh...I'd like to say that it was the first time too but that would be wrong.
Congrats on doing your first 2 injections. Freddd had a lot of peripheral nerve stuff. All I ever had was parathesia and only a mild case of that. All my symptoms were related to CFS and mental functioning.
My B12 injections are twice daily but in the beginning I was taking another 30 mg (got it right this time) spread throughout the day. Only this year has the mfolate intake decreased. When I was at your stage of recovery I was taking it many times a day, pouring a bit under the tongue.
The next time the needle gives you fog you might want to try that. Folate into the buccal pouch. If you have a bad reaction just rinse out your mouth and put a stop to the absorption.
@stridor
It's been a rough 2 1/2 days with shots! I think I have figured some things out and hoping for some input from you. I don't expect a reply on a Sunday night, but I can hope! I have to drive 45 minutes to town tomorrow for food, and need some kind of "normalizing" game plan to pull it off. I'm having brain fog, but will do my best to be as concise as possible.
Prior to shots I always did an approx 7am-1pm-7pm dose of MF followed by Enzy MB around 30 minutes later, most recently 1,500 mcg MF and 3,750 mcg MB each time (adding 3 mg AdB12 at 7pm dose). I don't have any trouble sleeping either with AdB or MB at night, probably due to hormone or adrenal drop, because I always unexpectedly pass out early while watching TV, then wake up after midnight-2am to put myself to bed.
10/6 - After 7pm MF took 1st 200 mcg MB shot (a little more than 5% of my current Enzy 7pm dose). Had some mild symptoms, as listed in previous post, but nothing big.
10/7 - 7am Since I felt about the same as usual when I woke up, possibly a little better, I decided to experiment with another shot. After 7am MF, I took 300 mcg MB shot this time. Way too strong! As mentioned in previous post I started feeling really keyed up in my brain followed by brain fog and other symptoms.
(
I'm getting ahead of myself, but it's important to note that I figured out on today 10/9 that it wasn't so much that the shot was too strong, but that I probably still had an active dose of MB in my system from the shot the night before! More details further on. I guess the pharmacist was wrong about the absorption rate? She was just guessing anyway. Previously another pharmacist told me the higher concentrations absorbed slower, so who knows?)
1pm - took regular dose of MF. I thought that would help because brain still feeling too keyed up from a.m. MB shot.
Started having probable overmethylation symptoms - started with burning skin in upper arms and upper back incl neck. (Btw. I get get paresthesia too, but mine is often a burning in the skin instead of prickling.) Then came heart palpitations and tight chest, and some anxiety over it. Maybe taking a smaller MF dose would have helped the MB "overdose" without causing overmethylation (
I never tried that before, but after your last post, I tried it today 10/9...read on.) Ate eggs and chocolate. Did not help.
1:55pm took regular dose of Enzys
Thought I started feeling a little better right away (maybe just anxiety better?), but still having heart palpitations. Burning skin a little better. Everything continuing to be better 10-20 min later, incl heart palpitations, feeling a bit more relaxed.
2:35pm still feel hot & slight heart palpitations, but a little jittery now from MB too! Now feel kind of tired too, somehow at the same time!
7pm - Did regular MF dose with no problem now. Decided to do another 200 mcg MB shot. Felt really amped up at first, dissipated somewhat after 1/2 hr, then felt fine by an hour or less.
10/8 - Woke up feeling kind of normal for me, except pain in legs and ankles
(figured out later it was symptoms of low potassium that were a problem for me at the startup of Freddd's protocol, but had been resolved since then by supplementing.)
7:30am - After regular MF dose, injected 200 mcg MB (decreased from 300 mcg yesterday a.m.) Took 6 min to taste and feel tongue/lip symptoms instead of feeling instantly this time.
10:30am - Feel tired and body feels heavy. Brain doesn't feel that sharp either.
11am - really tired, feel like crashing. Tried 1/4 Enzy, helped a little, but not much
11:25am -
Might be potassium! Ate can of wild Alaskan salmon (high in potassium) then took 4 more 99mg potassium. (Had already taken 3 potassium around 9:40am). 12:05pm - Feel better, but still don't like the way my brain feels, and still feel wobbly with sore legs/ankles. Prob didn't t need that 1/4 Enzy at 11am. Pretty sure it was low potassium, further evidence that the shot doses are stronger than my Enzy doses, and/or last much longer.
1:30pm - took regular MF dose, thankfully no overmethylation, followed by regular Enzy MB dose. Brain still doesn't feel great since a.m. shot though.
7:30pm - took regular MF followed by 200mcg MB shot. Didn't feel brightening for about half an hour, whereas felt right right away before. No negative effects.
10/9 - Woke up feeling ok then started feeling pretty good for me (body and brain), better than last 2 days.
7am - Took regular MF dose
7:45am - took regular Enzy MB dose (
not a shot this time). Immediately fell some tingling/prickling parasthesia in side/back of upper arms, followed by tingly legs.
Got the feeling the previous night's shot might still be working, because I don't usually have any symptoms from my normal a.m. doses of MF and Enzy MB! I could have probably waited until 1pm or 7pm to take anything!
8:50am - Really started feeling like too much MB - jittery, then started feeling out of it, disoriented, brain fog! Took Potassium & LCF but still feel the same.
I feel even worse than when I took the shot yesterday a.m.!
11:55am - after rereading your last post, I tried 1/4 of a 400 mcg Solgar MF (only 100mcg total) under tongue for brain fog. Immediately felt burning back of neck & upper arms and slight inc heartbeat/palpitations. Feel a little more relaxed mentally, but don't like the heart thing. Still some brain fog.
Maybe since I'm not MTHFR, the MF is not the antidote for my brain fog in the above scenario. Maybe the key is not to take too much MB, especially if the last shot is still working. However, if I only do 1 shot a day and don't take any MF in between, I am concerned that will turn off methylation. What do you think?
At least I've figured out that the shots last much longer than I thought! Maybe I only need 1 shot a day and possibly some MF and Enzy in between, but I have no idea how much or when. Do you have any thoughts on this?
I am planning to skip my 1pm MF/MB today and do my regular MF + 200 mcg MB shot at 7pm. Then skip a.m. dose tomorrow. I'm not sure whether to skip or take my regular 1pm MF/Enzy MB before I leave for town or not. I might have started feeling bad if I missed my 1pm dose by a few hours, but that was before the shots. I could bring some MF and Enzys with me if I skip it, but no idea how much to take or when. I've always done everything very systematically up until now. I am not the greatest at noticing subtle changes in my body, esp if I'm preoccupied hitting 3 stores grocery shopping.
I appreciate any input or ideas you might have! I wish I didn't have to go somewhere tomorrow in the middle of this, but no choice.
Lastly, what were your overmethylation symptoms the one time you had to take niacin?
Conversely, what symptoms do you get when you get low on MF and need to take it?
I really don't know what my low MF symptoms would be, other than possibly a tired shaky feeling I got a few times when I was a couple hours late for a regular MF/MB dose. I might have just needed LCF, I'm not sure. Brain fog is not one my symptoms for low MF as far as I know, but I've rarely been late for a dose. Before the bad EDTA reaction and Freddd's Protocol, the only time I usually got brain fog was from hormone fluctuations twice a month or from an allergic reaction. Now it's from either too much MF or MB, or both, but I don't always know which. In the past few days it seems like too much MB was the brain fog culprit, but the other side effects I've experienced from too much MF were slightly worse! That was the first time I think I've ever had overmethylation.