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AdB12 weird response?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by stridor, Sep 23, 2013.

  1. stridor

    stridor Senior Member

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    I hope that I can get my point across. I came here looking for answers to my remaining symptoms, the main one being brain-fog. At 20% of what it used to be - most of the time but sometimes worse.
    I am C677T ++ and that mfolate 800 - 1000 mcg daily
    I had a big improvement with mB12 injections 1 mg daily with some B vitamins (I call it my morning "B" sting).


    Following what I am learning here I started Ad B12 and it didn't do much. So I added carnitine and crashed on the second day. I will split the carnitine caps and try again next weekend. In the meantime, I continued with the adB12.

    So, today I am in a 3 1/2 hour yawn-fest meeting - you know the type - where you mind wanders all over the place. It dawned on me that adB12 was helping with that - as in able to concentrate. BUT - only while I had a chip in my mouth. 10 min after it was gone and I was losing track again. This improved focus occurred in the presence of brain-fog. That is the strange part. If you had asked me I would have told you the fog was different (had a weird pressure in my head) but that I was fogged. This is why I didn't pick up on it outside of the meeting setting.

    So now what? I have taken about 15 mg of adB12 today. Do I always keep a chip in my mouth? I thought with adB12 that I would just knock back a few until there were no more (+) returns and then only once every few days (?)
    How much of this stuff can I take? Or should I take if I am on 1 mg inj mB12 daily?

    Finally, (and thank-you for getting this far) can I become cobalt toxic from too much B12 or is the sky the limit?
    Thanks in advance for any help or stories about your AdB12 experience.
  2. stridor

    stridor Senior Member

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    OK. Today I went to work in the best shape in years in terms of brain-fog. Not hearing that there was any problems from respondents here, I kept pounding back the AdB12. Had a chip in my mouth most of the morning. At lunch I had dizziness. I had my first run-in with vertigo a month ago. It runs in my family with 4 siblings with some form of Meniere's or similar. This was not vertigo but it was more than a bit of dizziness. It was worse with head movement and I had some destabilization when I stood.
    I backed off the adB12 but think that dehydration was part of the problem...I drink less when I have a chip of B12 in my mouth all the time it seems.
    Feel better now but not back to baseline. Still dizzy when I move my head.
  3. stridor

    stridor Senior Member

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    Better today. Dizziness back to baseline. Didn't push as hard today with adB12. Sometimes it feels like I have stumbled onto the answer for me and brain-fog drops to 10% and at others it is back to 20%+ and I think that I am still missing a piece of the puzzle. Will introduce carnitine then eventually ubiquinol in small doses.
  4. stridor

    stridor Senior Member

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    So the above appears to be "start-up" symptoms only.
    Weird as I am on mB12 injections daily. I suppose that the enzyme that is supposed to convert MB12 to AdB12 is wonky. Haven't found the name of that enzyme yet. Anyway I am still responding to the AdB12 so I guess that means that I have yet to reach saturation.
  5. stridor

    stridor Senior Member

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    Today I have my "glutamate symptoms" increasing. These are anxiety, agitation and irritability. Nothing that I can't deal with but interesting as far as tracking progress goes.
  6. stridor

    stridor Senior Member

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    In case, as some have suggested that adb12 works best with carnitine, I'll introduce a bit. I am breaking my rules about how many things I am changing at once. Very hard to stick to this when certain supplements work in concert.

    Also, turning my focus back to choline. I have PEMT +- x 4 This one is for folate and choline transport and conversion of choline to pcholine. TYMS ++ that also is related to folate and choline somehow. MTHFD1 G1958A ++ that increases choline need. Because of these things I am supposed be a "bottomless pit" in terms of pcholine intake.

    In my recent purging of my pill line-up I decreased sunflower lecithin to 1 cap daily down from 4. Back up to 3 today.

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