My biggest struggle with methyl b12 is is makes my insomnia worse. Do you have any input? I don't seem to have this trouble with Hydroxy. The reason that mb12 does cause additional "stimulation" and hydroxycbl doesn't because mb12 is causing methylation to work and the nerves to be mnore active whereas the hycbl doesn't get these things working much at all and because mb12 has some conversion to adb12 allowing mitochondria to produce more energy which hycbl doesn't do as much. Mb12 of a 5 star brand is 100+ times more active than hycbl. I don't know of any way for these things to start up without starting up. They become NORMAL after they feel too wired for a little while. If you take a whole lot more mb12 your adjustment will happen far more quickly and may make only a little differnce in how is is subjectively. If you take enough adb12 that the adjust happens quickly then that part of it can be done with quickly. If you use only dribbles of mb12 iot could take months to years to get through it. If you keep increasing the dose looking for the maximum effect it will be over with much more quickly. Healing is dose proportionate but not linear. Perceived changes max out quickly and then you can increase the dose a lot more quickly bringing an end to change very quickly. When it no longer changes by taking mb12 but only maintains, it becomes "normal" quickly. I spent decades with sleep disorders of not being able to sleep more than 4-5 hours a night (pain and sleep disorders). I know what it is like to be up pacing at 3 am becasue lying down is too painful. If you get the mb12 working in your brain it corrects sleep disorders that it's lack causes. Metafolin restored dreaming to me after decades without.