Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Active b12 and folate dosage goal?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Lan Lan, Jan 16, 2014.

  1. Lan Lan

    Lan Lan


    I don't have chronic fatigue, but I believe I have mercury toxicity which could interfere with b12 metabolism. I read that people without b12 deficiency will not react to active b12 supplementation. What dosage does this refer to? Is there a dosage goal that one can test against? For example, I don't get the jittery reaction until I take up to 20mg of mb12. Does this signify that I am deficient or not?

    I have read from mercury chelation, that when one can tolerate 200mg ALA then it's an indicator that not much mercury is left in the system. I was wondering if there is something equivalent for b12 and folate? For example, a tolerable dosage to determine saturation and optimal level achieved?

    Lan Lan
  2. Soundthealarm21

    Soundthealarm21 Senior Member

    Dallas, TX
    20mg is an absolute ton.

    I think the easiest thing to do would be to have your doctor run blood tests.
  3. Freddd

    Freddd Senior Member

    Salt Lake City
    Hi LanLan,

    I think right there you have answered the question. A single tablet will cause a very noticeable response in the body if a person has all the other requirements. At least 25 % of the people art more deficient of AdoCbl, methylfolate and/or carnitine than of MeCbl. About 5% are more deficient of a another list of critical cofactors like Vit D, SAM-e, TMG, magnesium, zinc, Biotin, D-Ribose and a few more. However, at 20mg that looks like it could be a CNS response and that would be a yes for having a brain and cord deficiency.

    So if you would like to really find out then there is a lot more to do to get ready for your next body trial to give a the b12 a real chance, starting with the brand of MeCbl, how you used it, etc. And then we will be better able to try the CNS level again and see what was happening there. Right now it raises more questions than it answers.

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