The power and pitfalls of omics part 2: epigenomics, transcriptomics and ME/CFS
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Activated iron-containing microglia in the human hippocampus identified by MRI

Discussion in 'Other Health News and Research' started by Bob, Jul 22, 2015.

  1. Bob

    Bob

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    This came to my attention via Kathryn Stephens on Twitter.

    They think they have detected an increased amount of activated microglia in the hippocampus of Alzheimer’s patients (but, interestingly, not consistently in the same place as amyloid plaques or Tau proteins.)

    They hypothesise: "Neuropathologically, this suggests that microglial-mediated neurodegeneration may occur in the hippocampal formation in AD and is detectable by ultra-high resolution MRI."

    Iron-containing inflammatory cells seen in Alzheimer's brains
    Stanford University Medical Center
    July 20, 2015

    http://med.stanford.edu/news/all-ne...ammatory-cells-seen-in-alzheimers-brains.html

    Continue reading here:
    http://med.stanford.edu/news/all-ne...ammatory-cells-seen-in-alzheimers-brains.html
     
    Last edited: Jul 22, 2015
  2. Bob

    Bob

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    This is the research paper.

    Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease.
    Michael M. Zeineh, Yuanxin Chen, Hagen H. Kitzler, Robert Hammond, Hannes Vogel, Brian K. Rutt.
    Neurobiology of Aging. 2015.
    DOI: 10.1016/j.neurobiolaging.2015.05.022
    http://www.neurobiologyofaging.org/article/S0197-4580(15)00306-1/abstract
     
    aimossy likes this.
  3. Sidereal

    Sidereal Senior Member

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    Wasn't he the first author on the CFS DTI study out of Stanford recently?
     
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