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Acetyl l-carnitine and co q10 combo

Discussion in 'General Treatment' started by jayne73, Mar 20, 2017.

  1. jayne73

    jayne73

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    Hi this is my first post but I'm not new to CFS.
    I have started taking the following doses together: carnitine 1.5g and Q10 250mg. Within 20 minutes of taking these in the morning I get a surge of energy, this lasts for 4 hours before I come crashing down with extreme fatigue and heavy fog. I'm going to try spreading the doses out tomorrow but has anyone else experiencing this, I feel like absolute crap and can't function this afternoon. [​IMG]
     
  2. TiredSam

    TiredSam The wise nematode hibernates

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    Q10 blew my head off and made me feel really wierd. I read everything on PR that others had to say about it beforehand and was quite hopeful, but stopped within a couple of days.
     
  3. jayne73

    jayne73

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    Thanks for your reply. I tried the supplements seperately and neither had an effect. It was the combination of the two which had a massive improvement on my fatigue, I didn't feel wired but full of energy and really good but only for 4 hours. Did you feel worse after the q10 had worn off, I felt awful afterwards. I think I need to experiment a bit with the 2 supplements and hopefully find something that works for me.
     
  4. TiredSam

    TiredSam The wise nematode hibernates

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    I've just checked my notes. I took Q10 for two days, it made me dopey and headachey. I took 100 mg on the morning of day 1, and felt dizzy and very tired over the middle part of the day. On day 2, I took another 100 mg and again felt very tired over lunchtime and had a mild headache. My notes also say "great a.m.", which I suppose must mean that I had a good morning after taking the tablet, at least on day 2. It was last September. I stopped taking them and was back to how I normally feel the next day.
     
    Webdog likes this.
  5. CFS_for_19_years

    CFS_for_19_years คภภเє ɠรค๓թєl

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    Large doses of carnitine (2gm) suppress the thyroid, in fact, it is often used as a treatment for hyperthyroidism. More conservative amounts of carnitine such as 500mg won't have the same effect. It's possible you're getting a boost from the coQ10, followed by a thyroid-suppressing crash from the carnitine.
    Effects of carnitine on thyroid hormone action
    https://www.ncbi.nlm.nih.gov/pubmed/15591013
    Abstract
    Why not try them one at a time to see what's causing what?
     
    Helen likes this.

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